Results 51 to 60 of about 32,391 (255)

Citizen science informs human-tick exposure in the Northeastern United States

International Journal of Health Geographics, 2019
Background Tick-borne disease is the result of spillover of pathogens into the human population. Traditionally, literature has focused on characterization of tick-borne disease pathogens and ticks in their sylvatic cycles.
W. Tanner Porter, Peter J. Motyka, Julie Wachara, Zachary A. Barrand, Zahraa Hmood, Marya McLaughlin, Kelsey Pemberton, Nathan C. Nieto   +7 more
doaj   +1 more source

Persistence mechanisms in tick-borne diseases : tick-borne diseases

Onderstepoort J Vet Res, 2009
The use of new, highly sensitive diagnostic methods has revealed persistent infections to be a common feature of different tick-borne diseases, such as babesiosis, anaplasmosis and heartwater. Antigenic variation can contribute to disease persistence through the continual elaboration of new surface structures, and we know in several instances how ...
openaire   +3 more sources

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

Linking tick and wildlife host distributions to map risk of tick-borne diseases

Parasites & Vectors
Background Tick-borne pathogens threaten livestock worldwide, causing diseases such as anaplasmosis, babesiosis, heartwater and theileriosis in cattle. The epidemiology of each disease is complex, with multiple tick and/or host species interacting across
José-María García-Carrasco, David W. Crowder, Karen C. Poh, Juan Mosqueda, Massaro W. Ueti, Javier Gutierrez-Illan   +5 more
doaj   +1 more source

Tick-borne pathogen – Reversed and conventional discovery of disease

Frontiers in Public Health, 2014
Molecular methods have increased the number of known microorganisms associated with ticks significantly. Some of these newly identified microorganisms are readily linked to human disease while others are yet unknown to cause human disease.
Ellen eTijsse Klasen, Marion P.G. Koopmans, Hein eSprong   +2 more
doaj   +1 more source

Proteomic as an Exploratory Approach to Develop Vaccines Against Tick-Borne Diseases Using Lyme Borreliosis as a Test Case

Vaccines, 2020
Tick-borne diseases affecting humans and animals are on the rise worldwide. Vaccines constitute an effective control measure, but very few are available. We selected Lyme borreliosis, a bacterial infection transmitted by the hard tick Ixodes, to validate
Emilie Talagrand-Reboul, Benoit Westermann, Matthieu A. Raess, Gilles Schnell, Paola Cantero, Cathy Barthel, Laurence Ehret-Sabatier, Benoit Jaulhac, Nathalie Boulanger   +8 more
doaj   +1 more source

Spatial variation in risk for tick-borne diseases in residential areas of Dutchess County, New York.

PLoS ONE, 2023
Although human exposure to the ticks that transmit Lyme-disease bacteria is widely considered to occur around people's homes, most studies of variation in tick abundance and infection are undertaken outside residential areas.
Felicia Keesing, Emma Tilley, Stacy Mowry, Sahar Adish, William Bremer, Shannon Duerr, Andrew S Evans, Ilya R Fischhoff, Fiona Keating, Jennifer Pendleton, Ashley Pfister, Marissa Teator, Richard S Ostfeld   +12 more
doaj   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Editorial: ticks & tick-borne parasites and diseases

Parasitology
Ticks and tick-borne diseases affect humans, livestock, and wildlife in most regions of the globe. Although there are over 900 tick species globally, only approximately 10% of species are second to mosquitoes as major vectors of human and veterinary ...
Ala E. Tabor, Ala Tabor
doaj   +1 more source

Spatial clustering of fourteen tick species across districts of Zimbabwe

BMC Veterinary Research, 2021
Background Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of dollars through vaccine procurement ...
Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu, Daud Nyosi Ndhlovu   +6 more
doaj   +1 more source