Results 61 to 70 of about 69,379 (294)

Spatial variation in risk for tick-borne diseases in residential areas of Dutchess County, New York.

PLoS ONE, 2023
Although human exposure to the ticks that transmit Lyme-disease bacteria is widely considered to occur around people's homes, most studies of variation in tick abundance and infection are undertaken outside residential areas.
Felicia Keesing, Emma Tilley, Stacy Mowry, Sahar Adish, William Bremer, Shannon Duerr, Andrew S Evans, Ilya R Fischhoff, Fiona Keating, Jennifer Pendleton, Ashley Pfister, Marissa Teator, Richard S Ostfeld   +12 more
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Citizen science informs human-tick exposure in the Northeastern United States

International Journal of Health Geographics, 2019
Background Tick-borne disease is the result of spillover of pathogens into the human population. Traditionally, literature has focused on characterization of tick-borne disease pathogens and ticks in their sylvatic cycles.
W. Tanner Porter, Peter J. Motyka, Julie Wachara, Zachary A. Barrand, Zahraa Hmood, Marya McLaughlin, Kelsey Pemberton, Nathan C. Nieto   +7 more
doaj   +1 more source

Proteomic as an Exploratory Approach to Develop Vaccines Against Tick-Borne Diseases Using Lyme Borreliosis as a Test Case

Vaccines, 2020
Tick-borne diseases affecting humans and animals are on the rise worldwide. Vaccines constitute an effective control measure, but very few are available. We selected Lyme borreliosis, a bacterial infection transmitted by the hard tick Ixodes, to validate
Emilie Talagrand-Reboul, Benoit Westermann, Matthieu A. Raess, Gilles Schnell, Paola Cantero, Cathy Barthel, Laurence Ehret-Sabatier, Benoit Jaulhac, Nathalie Boulanger   +8 more
doaj   +1 more source

Spatial clustering of fourteen tick species across districts of Zimbabwe

BMC Veterinary Research, 2021
Background Ticks transmit several diseases that result in high morbidity and mortality in livestock. Tick-borne diseases are an economic burden that negatively affect livestock production, cost countries billions of dollars through vaccine procurement ...
Munyaradzi Davis Shekede, Silvester Maravanyika Chikerema, Moregood Spargo, Isaiah Gwitira, Samuel Kusangaya, Aldridge Nyasha Mazhindu, Daud Nyosi Ndhlovu   +6 more
doaj   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Editorial: ticks & tick-borne parasites and diseases

Parasitology
Ticks and tick-borne diseases affect humans, livestock, and wildlife in most regions of the globe. Although there are over 900 tick species globally, only approximately 10% of species are second to mosquitoes as major vectors of human and veterinary ...
Ala E. Tabor, Ala Tabor
doaj   +1 more source

Variable strength of forest stand attributes and weather conditions on the questing activity of Ixodes ricinus ticks over years in managed forests [PDF]

, 2013
Given the ever-increasing human impact through land use and climate change on the environment, we crucially need to achieve a better understanding of those factors that influence the questing activity of ixodid ticks, a major disease-transmitting vector ...
Kalko, Elisabeth, Ralf Lauterbach, Lauterbach, Ralf, Wells Konstans, O'Hara Robert B., Renner, S., O'Hara, R., Wells, Konstans, Elisabeth K V Kalko, Lauterbach Ralf, Kalko Elisabeth K. V., Wells, K., Kalko, E., Konstans Wells, Renner, Swen C., Robert B O'Hara, Renner, Swen Christoph, O'Hara, Robert B., Renner Swen C., Lauterbach, R., Kalko, Elisabeth K. V., Swen C Renner, Wells, Konstans L.   +22 more
core   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Mechanisms Affecting the Acquisition, Persistence and Transmission of Francisella tularensis in Ticks

Microorganisms, 2020
Over 600,000 vector-borne disease cases were reported in the United States (U.S.) in the past 13 years, of which more than three-quarters were tick-borne diseases.
Brenden G. Tully, Jason F. Huntley
doaj   +1 more source