Results 91 to 100 of about 44,700 (260)

Molecular Study of Sheep Malignant Theileriosis at Barka Region in the Sultanate of Oman

open access: yesIranian Journal of Parasitology, 2011
Background: We used the PCR technique based on the abovementioned primer pair and sequenc­ing to demonstrate the Theileria infection in the sheep samples collected from Sultanate of Oman.
P Shayan   +4 more
doaj  

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

open access: yesChemMedChem, Accepted Article.
InhA, an NAD‐dependent enoyl‐acyl carrier protein reductase, is involved in the biosynthesis of mycolic acids, specific lipids to mycobacteria. InhA is the target of isoniazid, a first‐line anti‐tuberculosis drug used since the 1950s. Isoniazid is a prodrug that needs to be activated by the catalase‐peroxidase KatG.
Julien Rizet   +7 more
wiley   +1 more source

Molecular detection of Anaplasma phagocytophilum in carrier cattle of Iran - first documented report

open access: yesIranian Journal of Microbiology, 2009
Background and Objectives: Anaplasma phagocytophilum is a zoonotic, tick borne rickettsial pathogen. A. phagocytophilum has been detected in North America, Europe, Africa and Asia by molecular methods.
V Noaman, P Shayan
doaj  

The Unique Phylogenetic Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin of the Genus Phlebovirus

open access: yesmSphere, 2018
The recent emergence of novel tick-borne RNA viruses has complicated the epidemiological landscape of tick-borne infectious diseases, posing a significant challenge to public health systems that seek to counteract tick-borne diseases.
Keita Matsuno   +15 more
doaj   +1 more source

Poultry Diseases Expert System using Dempster-Shafer Theory [PDF]

open access: yesarXiv, 2012
Based on World Health Organization (WHO) fact sheet in the 2011, outbreaks of poultry diseases especially Avian Influenza in poultry may raise global public health concerns due to their effect on poultry populations, their potential to cause serious disease in people, and their pandemic potential.
arxiv  

New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity

open access: yesChemMedChem, EarlyView.
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti   +13 more
wiley   +1 more source

Infusing Disease Knowledge into BERT for Health Question Answering, Medical Inference and Disease Name Recognition [PDF]

open access: yesarXiv, 2020
Knowledge of a disease includes information of various aspects of the disease, such as signs and symptoms, diagnosis and treatment. This disease knowledge is critical for many health-related and biomedical tasks, including consumer health question answering, medical language inference and disease name recognition. While pre-trained language models like
arxiv  

Expanding the Horizons of Phototherapy: A Review on the Superior Performance of Chalcogen‐Based Photosensitizers and Photothermal Agents for Cancer Therapy

open access: yesChemPhotoChem, EarlyView.
This review summarizes recent progress in chalcogen (S, Se, Te)‐incorporated photosensitizers and photothermal agent design. It explores synthetic strategies, spectroscopic and computational characterization, and in vitro/in vivo evaluations, showcasing the potential of these compounds for photodynamic and photothermal therapies.
Subhrakant Jena   +3 more
wiley   +1 more source

Computational Approaches for Disease Gene Identification [PDF]

open access: yesarXiv, 2017
Identifying disease genes from human genome is an important and fundamental problem in biomedical research. Despite many publications of machine learning methods applied to discover new disease genes, it still remains a challenge because of the pleiotropy of genes, the limited number of confirmed disease genes among whole genome and the genetic ...
arxiv  

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