Results 101 to 110 of about 60,770 (292)

Tick-borne encephalitis (TBE) [PDF]

open access: yes
Tick-borne encephalitis, or TBE, is a human viral infectious disease involving the central nervous system. TBE is caused by the tick- borne encephalitis virus (TBEV), a member of the family Flaviviridae, and was initially isolated in 1937.

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Molecular detection of Anaplasma phagocytophilum in carrier cattle of Iran - first documented report

open access: yesIranian Journal of Microbiology, 2009
Background and Objectives: Anaplasma phagocytophilum is a zoonotic, tick borne rickettsial pathogen. A. phagocytophilum has been detected in North America, Europe, Africa and Asia by molecular methods.
V Noaman, P Shayan
doaj  

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

open access: yesAdvanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun   +6 more
wiley   +1 more source

Growth of Cowdria ruminantium, the causative agent of heartwater, in a tick cell line

open access: yes, 2000
The tick-borne rickettsia Cowdria ruminantium has been propagated continuously for over 500 days in the Ixodes scapularis tick cell line IDE8 by using the Gardel isolate from bovine endothelial cells as an inoculum.
Sumption, Keith J   +3 more
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Northeastern China, a Hotspot for Tick-Borne Viral Diseases

open access: yesZoonoses
Northeastern China has a high incidence of tick-borne diseases. Emerging and re-emerging tick-borne viral diseases pose a considerable threat to public health.
Ziyan Liu, Zedong Wang
doaj   +1 more source

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao   +19 more
wiley   +1 more source

Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion

open access: yes, 2010
Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Gale, P.F.   +10 more
core   +1 more source

Realising Aboriginal Community Controlled Approaches to Child Reunification

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Reunification rates for Aboriginal and Torres Strait Islander children in out‐of‐home care (OOHC) in Australia are critically low, even though reunification is the preferred permanency outcome for children following removal, and despite a range of mechanisms and strategies ostensibly to support effective reunification. To better understand the
B. J. Newton   +4 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Tickborne diseases of the United States : a reference manual for health care providers. Sixth edition, 2022 [PDF]

open access: yes
Based on \u201cTickborne Diseases in Massachusetts: A Physician\u2019s Reference Manual,\u201d produced by collaboration between MDPH, Nancy Shadick, MD, MPH, and Nancy Maher, MPH of the RBB Arthritis and Musculoskeletal Diseases Clinical Research Center

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