Results 91 to 100 of about 60,770 (292)

Novel variants of tick-borne encephalitis virus from patient and tick samples in Norway [PDF]

The annual number of tick-borne encephalitis (TBE) cases in Norway has increased dramatically from 1 case in 1998 to 113 in 2023. Characterization of TBE virus (TBEV) genomes from both clinical samples and tick vectors is necessary to understand disease ...
Skudal, Hilde Kristin, Andreassen, Åshild K., Pettersson, John H.-O., Vikse, Rose, Lindstedt, Heidi Elisabeth Heggen, Sydow, Anita Koskela von, Andreassen, Åshild Kristine, Asghar, Naveed, Soleng, Arnulf, Maharjan, Urusha, Fevang, Borre, Alfsnes, Kristian, Bjerkreim, Randi Haukaas, Johansen, Wenche, Basnet, Suyog, Fevang, Børre, Bjerkreim, Randi, Von Sydow, Anita Koskela, Johansson, Magnus   +18 more
core   +1 more source

Application of Viral Metagenomics for Study of Emerging and Reemerging Tick-Borne Viruses

, 2020
Ticks are important vectors for different tick-borne viruses, some of which cause diseases and death in humans, livestock, and wild animals. Tick-borne encephalitis virus, Crimean-Congo hemorrhagic fever virus, Kyasanur forest disease virus, severe fever
Johansson Wensman, Jonas,, Sveriges lantbruksuniversitet., Berg, Mikael,   +2 more
core   +1 more source

AND‐Logic‐Gated Aptamer Switch for Precise Targeting and Regulation of RNA G‐Quadruplexes

Angewandte Chemie, EarlyView.
An AND‐logic‐gated aptamer switch enables tumor‐selective activation of RNA G‐quadruplex (rG4)‐targeting function. By combining cell‐surface recognition and intracellular redox sensing, the system achieves precise regulation of disease‐relevant RNA structures exclusively in tumor cells, with minimal off‐target effects in normal cells, offering a ...
Dan Wang, Ying Feng, Chun Kit Kwok
wiley   +2 more sources

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Tickborne diseases of the United States : a reference manual for health care providers. Fifth edition, 2018 [PDF]

Based on \u201cTickborne Diseases in Massachusetts: A Physician\u2019s Reference Manual,\u201d produced by collaboration between MDPH, Nancy Shadick, MD, MPH, andNancy Maher, MPH of the RBB Arthritis and Musculoskeletal Diseases Clinical Research Center ...

core  

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, EarlyView.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Tick-borne encephalitis virus in ticks detached from humans and follow-up of serological and clinical response.

, 2014
The risk of tick-borne encephalitis virus (TBEV) infection after a tick bite remains largely unknown. To address this, we investigated the presence of TBEV in ticks detached from humans in an attempt to relate viral copy number, TBEV subtype, and tick ...
Lindgren, Per-Eric, Nyman, Dag, Vene, Sirkka,, Wilhelmsson, Peter, Lindblom, Pontus,, Nyman, Dag,, Lindgren, Per-Eric,, Sjowall, Johanna, Haglund, Mats, Matussek, Andreas, Ernerudh, Jan, Andreassen, Åshild, Wilhelmsson, Peter,, Forsberg, Pia, Fryland, Linda, Vene, Sirkka, Fryland, Linda,, Matussek, Andreas,, Forsberg, Pia,, Ernerudh, Jan,, Haglund, Mats,, Andreassen, Åshild,, Lindblom, Pontus, Sjowall, Johanna,   +23 more
core   +1 more source

Molecular Study of Sheep Malignant Theileriosis at Barka Region in the Sultanate of Oman

Iranian Journal of Parasitology, 2011
Background: We used the PCR technique based on the abovementioned primer pair and sequenc­ing to demonstrate the Theileria infection in the sheep samples collected from Sultanate of Oman.
P Shayan, E Ebrahimzadeh, MH Tageldin, N Amininia, B Eckert   +4 more
doaj  

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source