Results 141 to 150 of about 75,529 (288)

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

A century of tick taxonomy in South Africa : tick-borne diseases

, 2009
Ivan G. Horak
openalex   +2 more sources

Connecting the Dots: Systems Thinking Highlights the Role of the Environment Sector in One Health Operationalization

Global Challenges, EarlyView.
This perspective highlights the need for a systems thinking approach in One Health to holistically address zoonotic disease prevention, and to strengthen connections with the environment sector for global pandemic preparedness. Abstract With One Health (OH) encompassing a holistic view of the interrelated health of humans, animals and environment ...
Alana Hansen, Anne‐Lise Chaber, Simon Reid, Adriana Milazzo   +3 more
wiley   +1 more source

Genome‐wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target

iMeta, EarlyView.
This study identifies the uncharacterized gene C9ORF50 as a novel regulator of immune evasion. Functioning as an intrinsically disordered protein, C9ORF50 drives liquid‐liquid phase separation to facilitate spliceosome assembly and maintain RNA splicing fidelity.
Tong Shao, Chuanyang Liu, Jingyu Kuang, Sisi Xie, Ying Qu, Yingying Li, Lulu Zhang, Fangzhou Liu, Yanhua Qi, Tao Hou, Ming Li, Sujuan Zhang, Yu Liu, Zhixiang Yuan, Jiali Liu, Yanming Hu, Jingyang Wang, Chenghu Song, Shaowei Zhang, Lingyun Zhu, Jianzhong Shao, Aifu Lin, Wenjun Mao, Guangchuan Wang, Lvyun Zhu   +24 more
wiley   +1 more source

Prenatal exposure to adverse life events and autism and autistic‐like traits in children in the Norwegian Mother, Father and Child Cohort Study (MoBa)

JCPP Advances, EarlyView.
Abstract Background Mothers' experience of adverse life events (ALEs, e.g., divorce, bereavement, injury) during pregnancy has been linked with neurodevelopmental conditions like autism, and related traits like social communication difficulties and repetitive behavior in children.
Aleksandra Kanina, Arvid Sjölander, Miriam I. Martini, Agnieszka Butwicka, Henrik Larsson, Amanda M. Hughes, Márta K. Radó, Mark J. Taylor, Alexandra Havdahl, Helga Ask, Mina A. Rosenqvist   +10 more
wiley   +1 more source

Trends in the control of theileriosis in sub-Saharan Africa : tick-borne diseases

, 2009
Declan J. McKeever
openalex   +2 more sources

In Vivo Evaluation of Hemiarthroplasty Bearing Materials Using Animal Models: A Scoping Review (Part II)

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is commonly used to treat damage localized to one side of a synovial joint, maximally preserving the patient's opposing healthy bone and cartilage; however, challenges remain due to accelerated wear of the cartilage articulating with the implant surface. This scoping review summarized investigations of hemiarthroplasty bearing
Landon M. Begin, Victoria P. Marino, Francesca De Vecchi, Douglas C. Moore, Markus A. Wimmer, Joseph J. Crisco   +5 more
wiley   +1 more source

Tick-borne encephalitis: immunological indicators of possible transformation of acute process into chronic disease

, 2010
Ye. I. Gusev, Тетяна Пархоменко, Valentina N. Buneva, O. B. Doronina, Visilii B. Doronin, И. И. Генералов, Б. М. Доронин, Georgy A. Nevinsky   +7 more
openalex   +2 more sources

The First Investigation of Tick Vectors and Tick-Borne Diseases in Extensively Managed Cattle in Alle District, Southwestern Ethiopia [PDF]

, 2020
Asrat Solomon Kenasew, Bereket Molla Tanga   +1 more
openalex   +1 more source

USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osimertinib (OSI) resistance in non‐small cell lung cancer (NSCLC) remains a significant challenge. This report explored the precise role of USP28 on OSI resistance in NSCLC and identified a functional downstream effector. OSI‐resistant H1975 cells (H1975/OSI) were established by long‐term OSI exposure.
Hu‐Sen Fan, Xiu‐Mei Li, Jia‐Qi Gu, Hai‐Feng Wang, Zhen‐Jiang Zhang   +4 more
wiley   +1 more source