Results 31 to 40 of about 51,593 (275)

Non-systemic transmission of tick-borne diseases: a network approach [PDF]

, 2016
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission. This occurs when tick gets the infection by co-feeding with infected ticks on the same host resulting in a direct pathogen transmission between the vectors, without infecting the ...
Bajardi, Paolo, Ferreri, Luca, Giacobini, Mario   +2 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

An in vitro model to assess the immunosuppressive effect of tick saliva on the mobilization of inflammatory monocyte-derived cells [PDF]

, 2015
Tick-borne pathogens cause potent infections. These pathogens benefit from molecules contained in tick saliva that have evolved to modulate host innate and adaptive immune responses.
A Frauenschuh, A Lanzavecchia, A Martin-Fontecha, A Sa-Nunes, A Skallova, Carinne Puech, CJ Oliveira, D Werling, DL Borjesson, Dominique Martinez, E Hodzic, E Shklovskaya, ES Trombetta, F Sallusto, GJ Randolph, GJ Randolph, GJ Randolph, GP Brooke, I Vancova, JC Hope, JM Ribeiro, JW Hovius, JW Hovius, M Deruaz, M Epardaud, M Guilliams, M Lopez-Bravo, Mathieu Epardaud, Nathalie Vachiery, PA Nuttall, Patricia Cavelier, R Garg, RM Steinman, Rosalie Aprelon, S Ochiai, SG Preston, Thierry Lefrançois, Valérie Rodrigues   +37 more
core   +4 more sources

Uptake and fecal excretion of Coxiella burnetii by Ixodes ricinus and Dermacentor marginatus ticks [PDF]

, 2020
Background: The bacterium Coxiella burnetii is the etiological agent of Q fever and is mainly transmitted via inhalation of infectious aerosols. DNA of C.
Henning, Klaus, Körner, Sophia, Makert, Gustavo R., Mertens‑Scholz, Katja, Nijhof, Ard M., Pfeffer, Martin, Starke, Alexander, Ulbert, Sebastian   +7 more
core   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Resilience in a noisy urban system

Regional Science Policy &Practice, EarlyView., 2023
Abstract The ability of cities to recuperate from disturbances and return to their evolutionary pathways depends, first and foremost, on the type of damage that the shock created. But in addition, it depends on how information is transmitted in the urban system and on how noise filters distort the information that reaches economic agents.
Dani Broitman, Daniel Czamanski
wiley   +1 more source

Tick-borne diseases and co-infection: Current considerations

Ticks and Tick-borne Diseases, 2021
Over recent years, a multitude of pathogens have been reported to be tick-borne. Given this, it is unsurprising that these might co-exist within the same tick, however our understanding of the interactions of these agents both within the tick and vertebrate host remains poorly defined.
Cutler, S. J., Vayssier-Taussat, M., Estrada-Peña, A., Potkonjak, A., Mihalca, A. D., Zeller, H.   +5 more
openaire   +2 more sources

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Investigation Into the Dynamics of the Cupula in the Vestibular Organ of Adult Zebrafish Using Metabolic Glycoengineering

Angewandte Chemie, EarlyView.
The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer, Andrea Jüngst, Verena F. Schöwe, Anne‐Katrin Gronewald, Valentin Wittmann   +4 more
wiley   +2 more sources

Clinical investigation on Theileria equi and Babesia caballi infections in Italian donkeys [PDF]

, 2015
Background: Interest in the welfare and diseases of donkeys is constantly increasing in several countries. Despite this, clinical research into donkeys needs to be in continual development since they show different reactions compared to horses in many ...
Beribe', Francesca, Cerquetella, Matteo, Fabrizia, Veronesi, Faillace, Vanessa, Laus, Fulvio, Meligrana, MARINA CONCETTA TERESA, Silvia, Ravagnan, Spaterna, Andrea, Tesei, Beniamino   +8 more
core   +4 more sources