Results 111 to 120 of about 41,007 (259)

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

BMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam, Xiaojun Cai, Malik Ihsan Ullah Khan, Robert Musiol, Quazi T. H. Shubhra   +4 more
wiley   +1 more source

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, EarlyView.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source

Dynamics of two pathogens in a single tick population

Letters in Biomathematics, 2019
A mathematical model for a two-pathogen, one-tick, one-host system is presented and explored. The goal of this model is to determine how long an invading pathogen persists within a tick population in which a resident pathogen is already established.
Alexis White, Elsa Schaefer, Chelsea Wright Thompson, Christopher M. Kribs, Holly Gaff   +4 more
doaj   +1 more source

IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection [PDF]

, 2017
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.Ixodes ricinus is the most widespread and abundant tick in Europe, frequently bites humans, and is the vector of several pathogens including ...
Bonnet, Sarah I., Fuente, José de la, Galindo, Ruth C., Liu, Xiang Ye   +3 more
core   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Tick-borne pathogens and their reservoir hosts in northern Italy

Ticks and Tick-borne Diseases, 2018
The aim of this study was to determine the occurrence of Anaplasma phagocytophilum, Rickettsia spp., Babesia spp., and Candidatus Neoehrlichia mikurensis in Ixodes spp. ticks removed from wildlife, domestic animals and humans in the Province of Trento (northern Italy) in order to better understand their ecology and provide public health professionals ...
Barakova, Ivana, Derdakova, M., Selyemova, D., Chvostac, M., Spitalska, E., Rosso, Fausta, Collini, Margherita, Rosa', Roberto, Tagliapietra, Valentina, Girardi, Matteo, Ramponi, C., Hauffe, Heidi Christine, Rizzoli, Annapaola   +12 more
openaire   +5 more sources

Identification of a novel ß-adrenergic octopamine receptor-like gene (ßAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks [PDF]

, 2016
Background: The cattle tick Rhipicephalus (Boophilus) microplus is an economically important parasite of livestock. Effective control of ticks using acaricides is threatened by the emergence of resistance to many existing compounds. Several continuous R.
Bell-Sakyi, Lesley, Cooper, Katherine, Jonsson, Nicholas N., Koh-Tan, Han Hui, Strachan, Erin   +4 more
core   +1 more source

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, EarlyView.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Identification of Rhipicephalus sanguineus sensu lato infected with tick-borne pathogens from pet and stray dogs in Guangzhou, Southern China

Ticks and Tick-Borne Diseases
Tick-borne diseases are of substantial concern worldwide for both humans and animals, and dogs are frequently exposed to tick infestation. The aim of this study was to examine tick infestation of pet and stray dogs in Guangzhou, Southern China, as well ...
Yuchen Wu, Yan Gao, Chao Tian, Jianbo Li, Liheng Wu, Haiyan Wang   +5 more
doaj   +1 more source

Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]

, 2010
Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A., EPIZONE (Funder), Fooks, A.R., Gale, P., Kelly, L., Kosmider, R., Ramnial, V., Snary, E.L.   +7 more
core   +1 more source