Results 1 to 10 of about 1,701,750 (216)

Electrochemical biosensors for pathogen detection

open access: yesBiosensors and Bioelectronics, 2020
Recent advances in electrochemical biosensors for pathogen detection are reviewed. Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and ...
Ellen Cesewski, Blake N Johnson
exaly   +2 more sources

Role of Protein Glycosylation in Host-Pathogen Interaction

open access: yesCells, 2020
Host-pathogen interactions are fundamental to our understanding of infectious diseases. Protein glycosylation is one kind of common post-translational modification, forming glycoproteins and modulating numerous important biological processes.
Borong Lin, Xue Qing, Jinling Liao
exaly   +2 more sources

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

open access: yesInternational Journal of Molecular Sciences, 2021
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF) contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its capacity to cause chronic infections.
Irene Jurado-Martín   +2 more
semanticscholar   +1 more source

SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness

open access: yesNature, 2020
A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to control the coronavirus disease 2019 (COVID-19) global pandemic.
Kizzmekia S. Corbett   +61 more
semanticscholar   +1 more source

Pathogen recognition and innate immunity.

open access: yesCell, 2006
Microorganisms that invade a vertebrate host are initially recognized by the innate immune system through germline-encoded pattern-recognition receptors (PRRs).
S. Akira, S. Uematsu, O. Takeuchi
semanticscholar   +1 more source

Rapid Pathogen Detection by Metagenomic Next-Generation Sequencing of Infected Body Fluids

open access: yesNature Medicine, 2020
We developed a metagenomic next-generation sequencing (mNGS) test using cell-free DNA from body fluids to identify pathogens. The performance of mNGS testing of 182 body fluids from 160 patients with acute illness was evaluated using two sequencing ...
W. Gu   +21 more
semanticscholar   +1 more source

Nextstrain: real-time tracking of pathogen evolution

open access: yesbioRxiv, 2017
Summary Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive ...
J. Hadfield   +8 more
semanticscholar   +1 more source

Action Mechanisms of Effectors in Plant-Pathogen Interaction

open access: yesInternational Journal of Molecular Sciences, 2022
Plant pathogens are one of the main factors hindering the breeding of cash crops. Pathogens, including oomycetes, fungus, and bacteria, secrete effectors as invasion weapons to successfully invade and propagate in host plants.
Shiyi Zhang   +4 more
semanticscholar   +1 more source

A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility

open access: yesCell, 2016
SUMMARY Despite the accepted health benefits of consuming dietary fiber, little is known about the mechanisms by which fiber deprivation impacts the gut microbiota and alters disease risk.
M. Desai   +15 more
semanticscholar   +1 more source

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

open access: yesScience, 2020
Tetrameric immune receptors Nucleotide-binding/leucine-rich repeat (NLR) immune receptors detect pathogen effectors and trigger a plant's immune response. Two groups have now defined the structures of two NLRs that carry Toll-like interleukin-1 receptor (
Raoul Martin   +7 more
semanticscholar   +1 more source

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