Background The growth and development of insects is strictly dependent on the precise regulation of chitin synthase (CHS), which is absent in vertebrates and plants. Therefore, CHS represents an attractive target for insecticides.
Xiaoshan Yang +7 more
doaj +1 more source
Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study [PDF]
BACKGROUND: Quantitative molecular methods (QMMs) such as quantitative real-time polymerase chain reaction (q-PCR), reverse-transcriptase PCR (qRT-PCR) and quantitative nucleic acid sequence-based amplification (QT-NASBA) are increasingly used to ...
A Gelman +56 more
core +4 more sources
Pathogen manipulation of chloroplast function triggers a light-dependent immune recognition [PDF]
In plants and animals, nucleotide-binding leucine-rich repeat (NLR) proteins are intracellular immune sensors that recognize and eliminate a wide range of invading pathogens.
Bozkurt, Tolga O. +13 more
core +1 more source
The pathology associated with Schistosoma japonicum (S. japonicum) infection in humans is attributed to parasite egg-induced granulomatous inflammation and fibrosis in the host liver.
Xiaojun Chen +13 more
doaj +1 more source
Blast disease in ryegrass is similar to rice blast in regard to infection cell biology [PDF]
Magnaporthe oryzae has been devastating to various grasses. This is especially true in food crops around the globe. Resistance has been implemented but has not been completely successful due to the variability of the fungus.
Dalby, Melinda +2 more
core
Screening of certain Ayurvedic plants extracts against E. turcicum [PDF]
The use of chemicals against pathogens is environmentally dangerous, so use of natural inhibitors for disease management is needed. In this work we screen botanical extracts from ayurvedic plants for their antifungal properties against economically ...
Kaushal Kumar Bhati +2 more
core +1 more source
Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens. [PDF]
BACKGROUND: Plants deploy immune receptors to detect pathogen-derived molecules and initiate defense responses. Intracellular plant immune receptors called nucleotide-binding leucine-rich repeat (NLR) proteins contain a central nucleotide-binding (NB ...
Cevik, Volkan +4 more
core +11 more sources
Parasitic antigens alter macrophage polarization during Schistosoma japonicum infection in mice
Background Schistosome eggs are trapped in host liver and elicit severe hepatic granulomatous inflammation, which can lead to periportal fibrosis, portal hypertension, hemorrhage, or even death in the host.
Jifeng Zhu +9 more
doaj +1 more source
Schistosoma japonicum infection causes a reprogramming of glycolipid metabolism in the liver
Background Recent investigations indicate that schistosome infection is closely associated with aberrant glycolipid metabolism. However, the actual glycolipid metabolism gene expression, as well as the possible pathways that regulate glycolipid ...
Zhi-Peng Xu +6 more
doaj +1 more source
Bacterial genomics reveal the complex epidemiology of an emerging pathogen in Arctic and boreal ungulates [PDF]
Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at ...
Amanda Niptanatiak +18 more
core +2 more sources

