Results 11 to 20 of about 2,673,378 (401)
Coevolutionary immune system dynamics driving pathogen speciation [PDF]
We introduce and analyze a within-host dynamical model of the coevolution between rapidly mutating pathogens and the adaptive immune response. Pathogen mutation and a homeostatic constraint on lymphocytes both play a role in allowing the development of ...
Carlson, Jean M. +2 more
core +35 more sources
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF) contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its capacity to cause chronic infections.
Irene Jurado-Martín +2 more
semanticscholar +1 more source
What makes pathogens pathogenic [PDF]
Metazoans contain multiple complex microbial ecosystems in which the balance between host and microbe can be tipped from commensalism to pathogenicity. This transition is likely to depend both on the prevailing environmental conditions and on specific gene-gene interactions placed within the context of the entire ecosystem.
Ehrlich, Garth D +2 more
openaire +2 more sources
MiR-279-3p regulates deltamethrin resistance through CYP325BB1 in Culex pipiens pallens
Background The overuse of insecticides to control insect vectors has promoted extensive insecticide resistance in mosquitoes. In this study, the functions of microRNA (miR)-279-3p and its target CYP325BB1 in the regulation of deltamethrin resistance in ...
Xixi Li +9 more
doaj +1 more source
Background Hepatic granuloma formation and fibrosis as the consequence of tissue entrapped eggs produced by female schistosomes characterize the pathology of Schistosoma japonicum infection.
Xueqi Bai +12 more
doaj +1 more source
MiR-4448 is involved in deltamethrin resistance by targeting CYP4H31 in Culex pipiens pallens
Background Culex pipiens (Cx. pipiens) complex, which acts as a vector of viruses and is widespread and abundant worldwide, including West Nile virus, Japanese encephalitis virus, and Sindbis virus, can cause serious vector-borne diseases affecting human
Xixi Li +8 more
doaj +1 more source
Background The pathogens transmitted by mosquitoes to humans and animals cause several emerging and resurgent infectious diseases. Increasing insecticide resistance requires rational action to control the target vector population. Chitin is indispensable
Xiaoshan Yang +8 more
doaj +1 more source
The ever increasing numbers of immunosuppressed individuals has led to a significant increase in the incidence of opportunistic infections, particularly those caused by fungi. The epidemiology of infections caused by the common fungal pathogens such as Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus has been well documented. However,
Ponton, J. +13 more
openaire +3 more sources
PECTOPLATE: the simultaneous phenotyping of pectin methylesterases, pectinases and oligogalacturonides in plants during biotic stresses [PDF]
Degradation of pectin, a major component of plant cell wall, is important for fungal necrotrophs to achieve a successful infection. The activities of pectin methylesterases (PMEs) from both plants and pathogens and the degree and pattern of pectin ...
LIONETTI, VINCENZO
core +8 more sources

