Results 11 to 20 of about 1,701,750 (216)

Oceanic Hitchhikers - Assessing Pathogen Risks from Marine Microplastic.

Trends in Microbiology, 2020
As plastic debris in the environment continues to increase, an emerging concern is the potential for microplastic to act as vectors for pathogen transport.
J. Bowley, C. Baker‐Austin, A. Porter, R. Hartnell, C. Lewis   +4 more
semanticscholar   +1 more source

Reactive Oxygen Species in Pathogen Clearance: The Killing Mechanisms, the Adaption Response, and the Side Effects

Frontiers in Microbiology, 2021
Reactive oxygen species (ROS) are attractive weapons in both antibiotic-mediated killing and host-mediated killing. However, the involvement of ROS in antibiotic-mediated killing and complexities in host environments challenge the paradigm.
Hao Li, Xuedong Zhou, Yuyao Huang, Binyou Liao, Lei Cheng, B. Ren   +5 more
semanticscholar   +1 more source

Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome

Science, 2019
Protecting plants from the inside out Some soils show a remarkable ability to suppress disease caused by plant pathogens, an ability that is attributed to plant-associated microbiota. Carrión et al.
V. Carrión, J. Pérez-Jaramillo, Viviane Cordovez, Vittorio Tracanna, M. de Hollander, Daniel Ruiz-Buck, L. Mendes, W. V. van Ijcken, Ruth Gomez-Exposito, S. Elsayed, Prarthana Mohanraju, Adini Q Arifah, J. van der Oost, J. Paulson, R. Mendes, G. V. van Wezel, M. Medema, J. Raaijmakers   +17 more
semanticscholar   +1 more source

Evidence for the plant recruitment of beneficial microbes to suppress soil-borne pathogen

bioRxiv, 2020
Emerging experimental framework suggests that plants under biotic stress may actively seek help from soil microbes, but empirical evidence underlying such a ‘cry for help’ strategy is limited.
Hongwei Liu, Jiayu Li, Lilia C. Cavalhais, Cassandra D. Percy, J. Verma, P. Schenk, B. Singh   +6 more
semanticscholar   +1 more source

Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes

Science, 2018
Defense cargo shuttles in vesicles Plants can use small RNAs (sRNAs) to interfere with virulence factor gene expression in pathogens. Cai et al. show that the small mustard plant Arabidopsis shuttles defensive sRNAs into the necrotrophic fungus Botrytis ...
Qiang Cai, Lulu Qiao, Ming Wang, Baoye He, F. Lin, Jared Palmquist, Sienna-Da Huang, Hailing Jin   +7 more
semanticscholar   +1 more source

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Annual Review of Pathology, 2018
Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive approach for pathogen detection. The cost of high-throughput or next-generation sequencing has been reduced by several orders of magnitude since its advent in 2004 ...
W. Gu, Steve Miller, C. Chiu
semanticscholar   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source