Results 31 to 40 of about 2,189,693 (359)

Targeting Antibiotic Tolerance, Pathogen by Pathogen [PDF]

Cell, 2018
Antibiotic tolerance, the capacity of genetically susceptible bacteria to survive the lethal effects of antibiotic treatment, plays a critical and underappreciated role in the disease burden of bacterial infections. Here, we take a pathogen-by-pathogen approach to illustrate the clinical significance of antibiotic tolerance and discuss how the ...
Meylan, Sylvain, Andrews, Ian W., Collins, James J.   +2 more
openaire   +4 more sources

Culex pipiens pallens cuticular protein CPLCG5 participates in pyrethroid resistance by forming a rigid matrix

Parasites & Vectors, 2018
Background Chemical insecticides have hugely reduced the prevalence of vector-borne diseases around the world, but resistance threatens their continued effectiveness.
Yun Huang, Qin Guo, Xiaohong Sun, Cheng Zhang, Na Xu, Yang Xu, Dan Zhou, Yan Sun, Lei Ma, Changliang Zhu, Bo Shen   +10 more
doaj   +1 more source

Autophagy vitalizes the pathogenicity of pathogenic fungi [PDF]

Autophagy, 2012
Plant pathogenic fungi utilize a series of complex infection structures, in particular the appressorium, to gain entry to and colonize plant tissue. As a consequence of the accumulation of huge quantities of glycerol in the cell the appressorium generates immense intracellular turgor pressure allowing the penetration peg of the appressorium to ...
Xiao-Hong, Liu, Hui-Min, Gao, Fei, Xu, Jian-Ping, Lu, Rodney J, Devenish, Fu-Cheng, Lin   +5 more
openaire   +2 more sources

Identification of proteins associated with pyrethroid resistance by iTRAQ-based quantitative proteomic analysis in Culex pipiens pallens

Parasites & Vectors, 2015
Background Mosquito control based on chemical insecticides is considered as an important element in the current global strategies for the control of mosquito-borne diseases.
Weijie Wang, Yuan Lv, Fujin Fang, Shanchao Hong, Qin Guo, Shengli Hu, Feifei Zou, Linna Shi, Zhentao Lei, Kai Ma, Dan Zhou, Donghui Zhang, Yan Sun, Lei Ma, Bo Shen, Changliang Zhu   +15 more
doaj   +1 more source

Plants for planting; indirect evidence for the movement of a serious forest pathogen, Teratosphaeria destructans, in Asia [PDF]

, 2011
Fungal diseases caused by native pathogens and pathogens introduced with planting stock have a significant impact on exotic plantation forestry in the tropics.
Wingfield, Michael J., Treena Burgess, Burgess, Treena I., Vera Andjic, Giles Hardy, Bernard Dell, Wingfield, M., Hardy, G., Paul Barber, Andjic, V., Barber, Paul A., Hardy, Giles E. St. J., Dell, Bernard (Bernie), Barber, P., Andjic, Vera, Dell, B., Michael Wingfield, Burgess, T.   +17 more
core   +1 more source

Action Mechanisms of Effectors in Plant-Pathogen Interaction

International Journal of Molecular Sciences, 2022
Plant pathogens are one of the main factors hindering the breeding of cash crops. Pathogens, including oomycetes, fungus, and bacteria, secrete effectors as invasion weapons to successfully invade and propagate in host plants.
Shi-Yi Zhang, Cong Li, Jinping Si, Zhigang Han, Donghong Chen   +4 more
semanticscholar   +1 more source

Killing them softly:managing pathogen polymorphism and virulence in spatially variable environments [PDF]

, 2013
Understanding why pathogen populations are genetically variable is vital because genetic variation fuels evolution, which often hampers disease control efforts.
Vale, Pedro F; id_orcid, Vale, Pedro F.
core   +1 more source

An association of Aquaporin-4 with the immunoregulation of liver pathology in mice infected with Schistosoma japonicum

Parasites & Vectors, 2015
Background Schistosomiasis is a chronic parasitic disease that affects approximately 200 million people. In Schistosomiasis japonica and mansoni, parasite eggs were trapped in host liver and stimulated the CD4+T cell responses to regulate the formation ...
Weiwei Zhang, Jifeng Zhu, Xian Song, Zhipeng Xu, Xue Xue, Xiaojun Chen, Xiaowei Yang, Yong Li, Xiaoxiao Dong, Sha Zhou, Wei Li, Yingying Qian, Feng Liu, Chuan Su   +13 more
doaj   +1 more source

ASGDB: a specialised genomic resource for interpreting Anopheles sinensis insecticide resistance

Parasites & Vectors, 2018
Background Anopheles sinensis is an important malaria vector in Southeast Asia. The widespread emergence of insecticide resistance in this mosquito species poses a serious threat to the efficacy of malaria control measures, particularly in China ...
Dan Zhou, Yang Xu, Cheng Zhang, Meng-Xue Hu, Yun Huang, Yan Sun, Lei Ma, Bo Shen, Chang-Liang Zhu   +8 more
doaj   +1 more source

Stenoparib, an Inhibitor of Cellular Poly(ADP-Ribose) Polymerase, Blocks Replication of the SARS-CoV-2 and HCoV-NL63 Human Coronaviruses In Vitro

mBio, 2021
New therapeutics are urgently needed in the fight against COVID-19. Repurposing drugs that are either already approved for human use or are in advanced stages of the approval process can facilitate more rapid advances toward this goal.
Nathan E. Stone, Sierra A. Jaramillo, Ashley N. Jones, Adam J. Vazquez, Madison Martz, Lora M. Versluis, Marlee O. Raniere, Haley E. Nunnally, Katherine E. Zarn, Roxanne Nottingham, Ken R. Ng, Jason W. Sahl, David M. Wagner, Steen Knudsen, Erik W. Settles, Paul Keim, Christopher T. French   +16 more
doaj   +1 more source