Results 41 to 50 of about 2,189,693 (359)

The phyllosphere microbiome shifts toward combating melanose pathogen

Microbiome, 2022
Plants can recruit beneficial microbes to enhance their ability to defend against pathogens. However, in contrast to the intensively studied roles of the rhizosphere microbiome in suppressing plant pathogens, the collective community-level change and ...
Pudong Li, Zeng-Rong Zhu, Yunzeng Zhang, Jianping Xu, Hong-Kai Wang, Zheng-Yi Wang, Hong-Ye Li   +6 more
semanticscholar   +1 more source

Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination [PDF]

, 2012
The intestinal immune system mounts inflammatory responses to pathogens but tolerates harmless commensal microbiota. Various mechanisms for pathogen/non-pathogen discrimination have been proposed but their general relevance for inflammation control is ...
Dirk Bumann (126124), Dirk Bumann, Yvonne Willer (126110), Willer, Yvonne, Willer Yvonne, Müller, Beatrice, Bumann, D., Yvonne Willer, Willer, Y., Beatrice Müller, Müller Beatrice, Müller, B., Bumann, Dirk, Bumann Dirk, Beatrice Müller (166158)   +14 more
core   +2 more sources

Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum

Parasites & Vectors, 2017
Background The involvement of CD8+T cells in schistosomiasis is being increasingly appreciated, but the underlying mechanism is not well defined. Results In this study, we showed that the absence of Batf3 alleviated liver damage in Batf3 −/− mice ...
Lin Chen, Donghui Zhang, Wenyue Zhang, Yuxiao Zhu, Min Hou, Bingya Yang, Zhipeng Xu, Minjun Ji, Guanling Wu   +8 more
doaj   +1 more source

A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility

Cell, 2016
SUMMARY Despite the accepted health benefits of consuming dietary fiber, little is known about the mechanisms by which fiber deprivation impacts the gut microbiota and alters disease risk.
M. Desai, Anna M. Seekatz, N. Koropatkin, N. Kamada, C. A. Hickey, Mathis Wolter, Nicholas A. Pudlo, Sho Kitamoto, N. Terrapon, Arnaud Muller, V. Young, B. Henrissat, P. Wilmes, T. Stappenbeck, G. Núñez, E. Martens   +15 more
semanticscholar   +1 more source

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

Science, 2020
Tetrameric immune receptors Nucleotide-binding/leucine-rich repeat (NLR) immune receptors detect pathogen effectors and trigger a plant's immune response. Two groups have now defined the structures of two NLRs that carry Toll-like interleukin-1 receptor (
Raoul Martin, Tiancong Qi, Haibo Zhang, Furong Liu, Miles King, C. Toth, E. Nogales, B. Staskawicz   +7 more
semanticscholar   +1 more source

Balancing Selection at the Tomato RCR3 Guardee Gene Family Maintains Variation in Strength of Pathogen Defense [PDF]

, 2012
Coevolution between hosts and pathogens is thought to occur between interacting molecules of both species. This results in the maintenance of genetic diversity at pathogen antigens (or so-called effectors) and host resistance genes such as the major ...
Anja C. Hörger, Rose, Laura E., Renier A. L. Van Der, Renier A. L. van der Hoorn (150148), Van Der Hoorn, RAL, van der Hoorn, RA, Hoerger, A., Rose, LE, Van der Hoorn, R., Muhammad Ilyas, Laura E Rose, Ilyas, M, Laura E. Rose (150153), Hörger, Anja C., Laura E. Rose, Hoerger, AC, Rose, L., Aurélien Tellier, Van Der Hoorn, Renier, Stephan, Wolfgang, Hörger, AC, Tellier, A, Tellier, A., Muhammad Ilyas (150134), Anja C Hörger, van der Hoorn, Renier A. L., Anja C. Hörger (150127), Tellier, Aurélien, Stephan, W., Wolfgang Stephan (14960), Aurélien Tellier (150142), Renier A L van der Hoorn, Wolfgang Stephan, Stephan, W, Ilyas, M., Ilyas, Muhammad, van der Hoorn Renier A. L., Rose Laura E., Tellier Aurélien, Stephan Wolfgang, Hörger, Anja C.;Ilyas, Muhammad;Stephan, Wolfgang;Tellier, Aurélien;van der Hoorn, Renier A. L.;Rose, Laura E., Ilyas Muhammad, Hörger Anja C.   +42 more
core   +2 more sources

Viral pathogens [PDF]

Haemophilia, 2010
Summary.  Despite continuous improvement in safety and purity of blood products for individuals with haemophilia, transmissible agents continue to affect individuals with haemophilia. This chapter addresses three viral pathogens with significant clinical impact: HIV, hepatitis C and parvovirus B19.
M V, Ragni, K E, Sherman, J A, Jordan
openaire   +2 more sources

Praziquantel treatment after Schistosoma japonicum infection maintains hepatic insulin sensitivity and improves glucose metabolism in mice

Parasites & Vectors, 2017
Background Epidemiological studies in China have revealed that Schistosoma japonicum infection is inversely correlated with metabolic syndrome, even after repeated chemotherapy with praziquantel (PZQ). We investigated the effect of chronic S.
Xiaofeng Luo, Yuxiao Zhu, Ran Liu, Jingwei Song, Fan Zhang, Wenyue Zhang, Zhipeng Xu, Min Hou, Bingya Yang, Lin Chen, Minjun Ji   +10 more
doaj   +1 more source

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

Annual Review of Pathology, 2018
Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive approach for pathogen detection. The cost of high-throughput or next-generation sequencing has been reduced by several orders of magnitude since its advent in 2004 ...
W. Gu, Steve Miller, Charles Y. Chiu
semanticscholar   +1 more source

Oceanic Hitchhikers - Assessing Pathogen Risks from Marine Microplastic.

Trends in Microbiology, 2020
As plastic debris in the environment continues to increase, an emerging concern is the potential for microplastic to act as vectors for pathogen transport.
J. Bowley, C. Baker-Austin, A. Porter, R. Hartnell, C. Lewis   +4 more
semanticscholar   +1 more source