Results 141 to 150 of about 495,246 (243)

Transcriptomic and Metabolomic Profiling Identifies a Core Gene–Metabolite Axis Driving African Swine Fever Virus Replication in the Soft Tick Ornithodoros lahorensis

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Transcriptomic and metabolomic profiling of Ornithodoros lahorensis during African swine fever virus (ASFV) infection reveals that ASFV rewires host purine/pyrimidine metabolism, lipid metabolism, and energy metabolism. A core gene‐metabolite regulatory axis consisting of 12 key genes and 8 signature metabolites is identified to support viral genome ...
Jin Luo   +9 more
wiley   +1 more source

Severe fever with thrombocytopenia syndrome virus infection shapes gut microbiome of the tick vector Haemaphysalis longicornis

open access: yesParasites & Vectors
Background Ticks serve as vectors for a diverse array of pathogens, including viruses responsible for both human and livestock diseases. Symbiotic bacteria hold significant potential for controlling tick-borne disease. However, the alteration of tick gut
Yu Sun   +5 more
doaj   +1 more source

Potential Mechanisms of Transmission of Tick-Borne Viruses at the Virus-Tick Interface. [PDF]

open access: yesFront Microbiol, 2022
Maqbool M   +20 more
europepmc   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner   +5 more
wiley   +1 more source

Exploring the potential of tick transcriptomes for virus screening: A data reuse approach for tick-borne virus surveillance.

open access: yesPLoS Neglected Tropical Diseases
BackgroundWe set out to investigate the utility of publicly available tick transcriptomic data to identify and characterize known and recently described tick-borne viruses, using de novo assembly and subsequent protein database alignment and taxonomical ...
Koray Ergunay   +2 more
doaj   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

open access: yesVeterinary Record, Volume 199, Issue 5, Page e238-e249, 5/12 September 2026.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson   +2 more
wiley   +1 more source

Evaluation of two artificial infection methods of live ticks as tools for studying interactions between tick-borne viruses and their tick vectors. [PDF]

open access: yesSci Rep, 2022
Migné CV   +11 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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