Results 241 to 250 of about 469,795 (310)
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
Blood plasma proteomics for detecting potential biomarkers for tick resistance in a tropically adapted beef cattle breed. [PDF]
Abduch NG +7 more
europepmc +1 more source
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang +15 more
wiley +1 more source
Transcriptomics insights into the functional role of tick Ixodes ricinus proteins metalloprotease and antigen p23. [PDF]
Vaz-Rodrigues R +3 more
europepmc +1 more source
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing +7 more
wiley +1 more source
Neoehrlichia mikurensis in Ticks and Tick-Bitten Persons, Sweden and Finland, 2008-2009. [PDF]
Hero E +5 more
europepmc +1 more source

