Results 41 to 50 of about 112,004 (274)
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling +6 more
wiley +1 more source
Disulfiram: Mechanisms, Applications, and Challenges
Antibiotics, 2023 Background: Since disulfiram’s discovery in the 1940s and its FDA approval for alcohol use disorder, other indications have been investigated. This review describes potential clinical applications, associated risks, and challenges.
Jenna Lanz +5 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell +10 more
wiley +1 more source
Microbial Cell Factories, 2018 Background Tannases are tannin-degrading enzymes that have been described in fungi and bacteria as an adaptative mechanism to overcome the stress conditions associated with the presence of these phenolic compounds.
Julen Tomás-Cortázar +10 more
doaj +1 more source
Pathogens, 2023 The blacklegged tick, Ixodes scapularis, is the predominant vector of Borrelia burgdorferi, the agent of Lyme disease in the USA. Natural hosts of I. scapularis such as Peromyscus leucopus are repeatedly infested by these ticks without acquiring tick ...
Sukanya Narasimhan +4 more
doaj +1 more source
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Advanced Biology, EarlyView.Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André +3 more
wiley +1 more source
Ticks and Tick-Borne Diseases, 2023 The Amblyomma genus is represented on the African continent by 24 species, out of which 17 are known to occur in different ecological niches of southern Africa. Amblyomma, known for their aggressive hunting behaviour and aptitude as pathogen vectors, are
Andeliza Smit +6 more
doaj
A Computer Vision Approach to Combat Lyme Disease [PDF]
arXiv, 2020 Lyme disease is an infectious disease transmitted to humans by a bite from an infected Ixodes species (blacklegged ticks). It is one of the fastest growing vector-borne illness in North America and is expanding its geographic footprint. Lyme disease treatment is time-sensitive, and can be cured by administering an antibiotic (prophylaxis) to the ...
arxiv
Ticking clocks in quantum theory [PDF]
arXiv, 2023 We present a derivation of the structure and dynamics of a ticking clock by showing that for finite systems a single natural principle serves to distinguish what we understand as ticking clocks from time-keeping systems in general. As a result we recover the bipartite structure of such a clock: that the information about ticks is a classical degree of ...
arxiv
Advanced Functional Materials, EarlyView.This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong +11 more
wiley +1 more source