Results 41 to 50 of about 61,826 (298)

Lyme arthritis: Demographic characteristics and Borrelia ospA genospecies in synovial fluid. A 17-year cohort study in Sweden

Ticks and Tick-Borne Diseases
Lyme arthritis (LA) is a recognized manifestation of Lyme borreliosis in Sweden, but data on the causative Borrelia species are limited. This study aimed to describe the demographics of LA and identify Borrelia burgdorferi sensu lato (B. burgdorferi s.l.)
Katharina Ornstein, Camilla Broholm, Ram B. Dessau, Ann-Cathrine Petersson   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Brazil's battle against Rhipicephalus (Boophilus) microplus ticks: current strategies and future directions

Revista Brasileira de Parasitologia Veterinária
Ticks are parasitic arthropods that cause significant economic losses to livestock production worldwide. Although Rhipicephalus (Boophilus) microplus, the cattle tick, occurs throughout the Brazilian territory, there is no official program to control ...
Guilherme Marcondes Klafke, Patrícia Silva Golo, Caio Marcio Oliveira Monteiro, Lívio Martins Costa-Júnior, José Reck   +4 more
doaj   +1 more source

Evaluation of tick control tube month of placement and modifications to increase visitation by small mammals

Ecosphere, 2022
Tick control tubes are a host‐targeted tick control method targeting immature Ixodes scapularis ticks attached to mice or found within mouse burrows and nests.
Kylie D. Green, Hannah S. Tiffin, Jessica E. Brown, Edwin R. Burgess IV, Erika T. Machtinger   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Antiplasmodial activity of tick defensins in a mouse model of malaria

, 2022
S.844-849Malaria is a mosquito-borne disease affecting millions of people mainly in Sub-Saharan Africa, Asia and some South American countries. Drug resistance to first-line antimalarial drugs (e.g. chloroquine, sulfadoxine-pyrimethamine and artemisinin)
Vilcinskas, A., Cabezas-Cruz, A., Domingos, A., Antunes, S., Couto, J., Fuente, J. de la, Ferrolho, J., Tonk, M.   +7 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Mini Review: Current tick control strategies in Pakistan are possible environmental risks [PDF]

Iraqi Journal of Veterinary Sciences, 2017
Ticks infestation is the major problem of cattle and buffalo of Pakistan. Tick acts as vectors of many viral, protozoal and bacterial diseases and Crimean-Congo Haemorrhagic Fever (CCHF) is one of the most lethal in that list.
A. Iqbal, M. Usman, M. Abubakar
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Modelling the transmission dynamics of Theileria annulata : model structure and validation for the Turkish context [PDF]

, 2012
A mathematical model that describes the transmission dynamics of Theileria annulata is proposed that consists of 2 host components: the Hyalomma tick population and a compartmental model of T. annulata infection in the cattle population.
Sutton, AJ, Medley, GF, Karagenc, T., Sarali, H, Pekel, G., Sutton, Andrew, Bakirci, S, Sarali, H., Medley, Graham, Bakirci, S., Sutton, A. J., Pekel, G, Karagenc, T   +12 more
core   +1 more source