Results 51 to 60 of about 9,864,889 (296)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Willingness and capacity of publicly-funded vector control programs in the USA to engage in tick management

Parasites & Vectors
Background The vast majority of vector-borne diseases in the USA are associated with mosquitoes or ticks. Mosquito control is often conducted as part of community programs run by publicly-funded entities.
James C. Burtis, Erik Foster, Rebecca J. Eisen, Lars Eisen   +3 more
doaj   +1 more source

Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission

Frontiers in Cellular and Infection Microbiology, 2017
New tick and tick-borne pathogen control approaches that are both environmentally sustainable and which provide broad protection are urgently needed. Their development, however, will rely on a greater understanding of tick biology, tick-pathogen, and ...
Adrien A. Blisnick, Thierry Foulon, Sarah I. Bonnet   +2 more
doaj   +1 more source

Suitability of GWAS as a Tool to Discover SNPs Associated with Tick Resistance in Cattle: A Review

Pathogens, 2021
Understanding the biological mechanisms underlying tick resistance in cattle holds the potential to facilitate genetic improvement through selective breeding.
Nelisiwe Mkize, Azwihangwisi Maiwashe, Kennedy Dzama, Bekezela Dube, Ntanganedzeni Mapholi   +4 more
doaj   +1 more source

Ticks and Their Control.

, 2020
This book chapter describes the most common control methods: the use of genetically resistant animals and the application of acaricides. Acaricides may be applied through dips, sprays or pour-on formulations as well as intra-ruminal boluses, ear tagscand footbaths.
openaire   +2 more sources

Implicaciones del Tick en la calidad de las bolsas [PDF]

, 2003
El objetivo principal del presente trabajo es analizar el papel jugado por el tick en distintos mercados con el fin de entender mejor el proceso de intercambio bajo precios discretos y las importantes implicaciones que dicho entendimiento debe producir ...
Tapia Torres, Miguel Ángel, Tapia, Mikel, Abad, David   +2 more
core   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African ixodid tick species [PDF]

, 2016
Background: The tick population of Africa includes several important genera belonging to the family Ixodidae. Many of these ticks are vectors of protozoan and rickettsial pathogens including Theileria parva that causes East Coast fever, a debilitating ...
Olds, C., Pflüger, V., Stephen Mwaura, Julian Rothen, Cassandra Olds, Bishop, Richard P., Daubenberger, C.A., Richard P. Bishop, Olds, Cassandra L., Pflueger, V., Esther G. Kanduma, Githaka, Naftaly W., Daubenberger, C., Rothen, J., Valentin Pflüger, Githaka, N., KAnduma, E. G., Mwaura, S., Bishop, R. P., Naftaly Githaka, Claudia Daubenberger, Kanduma, Esther G., Olds C, Daubenberger C, Githaka N, Mwaura S, Bishop RP, Rothen J, Kanduma EG, Pflüger V   +29 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source