Results 41 to 50 of about 38,947 (226)

Immediate efficacy and persistent speed of kill of a novel oral formulation of afoxolaner (NexGardTM) against induced infestations with Ixodes ricinus ticks

Parasites & Vectors, 2014
Background Ticks are hematophageous arthropods that transmit a wide spectrum of pathogens to human and animals. The ability of an acaricidal product to kill ticks quickly provides an important added benefit, especially as protecting dogs from tick bites ...
Lénaïg Halos, Wilfried Lebon, Karine Chalvet-Monfray, Diane Larsen, Frederic Beugnet   +4 more
doaj   +1 more source

A Vaccinomics Approach for the Identification of Tick Protective Antigens for the Control of Ixodes ricinus and Dermacentor reticulatus Infestations in Companion Animals

Frontiers in Physiology, 2019
Ticks and tick-borne pathogens affect health and welfare of companion animals worldwide, and some human tick-borne diseases are associated with exposure to domestic animals. Vaccines are the most environmentally friendly alternative to acaracides for the
Marinela Contreras, Margarita Villar, José de la Fuente, José de la Fuente   +3 more
doaj   +1 more source

A 454 survey of the community composition and core microbiome of the common bed bug, Cimex lectularius, reveals significant microbial community structure across an urban landscape [PDF]

, 2012
Elucidating the spatial dynamic and core constituents of the microbial communities found in association with arthropod hosts is of crucial importance for insects that may vector human or agricultural pathogens.
Baucom, Regina S, Matthews, Sara, Meriweather, Matthew, Rio, Rita   +3 more
core   +6 more sources

A review on Hyalomma species infestations on human and animals and progress on management strategies

Heliyon, 2020
The Hyalomma species of ticks have gained additional attention due to their role in the transmission of Theileria annulata infection in animals and the Crimean-Congo Haemorrhagic Fever (CCHF) virus in humans.
Binod Kumar, Haranahally Vasanthachar Manjunathachar, Srikanta Ghosh   +2 more
doaj   +1 more source

Efficacy of fluralaner chewable tablets (Bravecto®) against Asian longhorned tick (Haemaphysalis longicornis) infestations of dogs

Parasites & Vectors, 2023
Background The parthenogenic reproductive ability of Haemaphysalis longicornis, facilitating quick life cycle completion and rapid geographic spread and its pathogen vector potential make infestations a risk to human and canine health. Two 90-day studies
Melissa Petersen, Riaan Maree, Alta Viljoen, Julian E. Liebenberg, Frank Guerino   +4 more
doaj   +1 more source

Impact of the Paper by Allen and Humphreys (1979) on Anti-Tick Vaccine Research

Pathogens, 2022
The classic paper by Allen and Humphreys “Immunisation of guinea pigs and cattle against ticks” Nature, 1979, 280: 491–493 led to a surge in the development of tick vaccines as a nonchemical method for prevention of tick infestations in susceptible hosts
Consuelo Almazán
doaj   +1 more source

Transcriptional profiling of the murine cutaneous response during initial and subsequent infestations with Ixodes scapularis nymphs [PDF]

, 2012
Background Ixodes scapularis ticks are hematophagous arthropods capable of transmitting many infectious agents to humans. The process of blood feeding is an extended and continuous interplay between tick and host responses.
Dar M Heinze, Stephen K Wikel, Saravanan Thangamani, Francisco J Alarcon-Chaidez   +3 more
core   +2 more sources

Incidents of high tick load in injured cheetahs after reintroduction into a tropical ecosystem

Onderstepoort Journal of Veterinary Research
Ectoparasites can severely impact wildlife species, both through their feeding behaviour and by facilitating secondary infestations or bacterial infections. Here, we report on two cases of periorbital damage caused by ixodid tick infestations in cheetahs
Tamar A. Kendon, Carlos L. Pereira, Hugo Pereira, Kelsey Brown, David Gaynor, Willem D. Briers-Louw   +5 more
doaj   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Modeling the impact of climate and landscape on the efficacy of white tailed deer vaccination for cattle tick control in northeastern Mexico. [PDF]

PLoS ONE, 2014
Cattle ticks are distributed worldwide and affect animal health and livestock production. White tailed deer (WTD) sustain and spread cattle tick populations.
Agustín Estrada-Peña, Diana Carreón, Consuelo Almazán, José de la Fuente   +3 more
doaj   +1 more source