Results 121 to 130 of about 215,327 (355)

Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks

open access: yesAdvanced Functional Materials, EarlyView.
Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert   +10 more
wiley   +1 more source

Simulations of Antigenic Variability in Influenza A [PDF]

open access: yes, 2008
Computational models of the immune system (IS) and pathogenic agents have several applications, such as theory testing and validation, or as a complement to first stages of drug trials.
Agostinho C. Rosa   +2 more
core   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

open access: yesAdvanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter   +5 more
wiley   +1 more source

Análise sistêmico-funcional como suporte para a leitura de textos: o caso da cerveja Devassa Systemic-functional analysis as support for reading of texts: the "Devassa" case

open access: yesRevista Brasileira de Linguística Aplicada, 2012
Partindo do conceito de leitura como um processo que permite ao leitor colocar em relação um discurso com discursos prévios, este trabalho busca ilustrar como a análise subsidiada por categorias propostas pela teoria sistêmicofuncional permite ...
Cristiane Fuzer   +2 more
doaj  

Efficient Analysis of Complex Diagrams using Constraint-Based Parsing

open access: yes, 1995
This paper describes substantial advances in the analysis (parsing) of diagrams using constraint grammars. The addition of set types to the grammar and spatial indexing of the data make it possible to efficiently parse real diagrams of substantial ...
Futrelle, Robert P., Nikolakis, Nikos
core   +4 more sources

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

open access: yesAdvanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka   +2 more
wiley   +1 more source

Evaluation of Nanonanoliposomal Curcumin on Cutaneous Leishmaniasis Skin Lesions Caused by Leishmania major in BALB/c Mice

open access: yesIranian Journal of Parasitology
Background: Curcumin is an extract of rhizome turmeric (diferuloylmethane), with antioxidant, anti-inflammatory, antimicrobial, and anti-parasitic properties, which making it a potential candidate for the treatment of leishmaniasis.
Sedigheh Shirmohammad   +6 more
doaj  

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

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