Results 131 to 140 of about 145,686 (240)

Structure, Mechanics, and Mechanobiology of Fibrocartilage Pericellular Matrix Mediated by Type V Collagen

Advanced Science, EarlyView.
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang, Mingyue Fan, Su Chin Heo, Sheila M. Adams, Thomas Li, Yuchen Liu, Qing Li, Claudia Loebel, Jason A. Burdick, X. Lucas Lu, David E. Birk, Farid Alisafaei, Robert L. Mauck, Lin Han   +13 more
wiley   +1 more source

Contact between soft tick vectors of African swine fever virus and invasive wild pigs in the southeastern USA. [PDF]

Parasit Vectors
Wisely SM, Torhorst C, Botero-Cañola S, Canino N, James AM, O'Hara KC.   +5 more
europepmc   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao, Zhili Wang, Hyoyong Kim, Hui Kong, Junseok Lee, Jacqueline Ziqian Yang, Anmin Wang, Ryan Y. Zhang, Yong Ju, Jina Kim, Bing Feng, Dejun Liu, Yating Zhang, Zhenfang Wang, Yandong Zhang, Shujing Guo, Dekang Gao, James S. Tomlinson, Renjun Pei, Jipeng Wan, Stephen J. Pandol, Myung‐Shin Sim, Sungyong You, Ding Ma, Shaohua Lu, Na Sun, Hsian‐Rong Tseng, Yazhen Zhu   +27 more
wiley   +1 more source

MicroRNA-34-5p regulates the expression of ecdysteroid receptor (ECR) in the process of salivary gland degeneration of ticks. [PDF]

Parasit Vectors
Hu S, Wang Y, Zhou Y, Cao J, Zhang H, Zhou J.   +5 more
europepmc   +1 more source

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang   +7 more
wiley   +1 more source

Molecular detection of novel Jingmen tick virus in hard ticks from diverse hosts in Guangxi, southwestern China. [PDF]

Virol J
Chen P, Wei X, Que T, Yan T, Li S, Zhong Y, Li Y, He M, Liu W, Hu Y.   +9 more
europepmc   +1 more source

Noninvasive Assessment of β‐Secretase Activity Through Click Chemistry‐Mediated Enrichment of Neuronal Extracellular Vesicles to Detect Alzheimer's Disease

Advanced Science, EarlyView.
This study presents the NEV β‐secretase activity assay, a groundbreaking method for noninvasive evaluation of β‐secretase activity in Alzheimer's disease (AD) patients, enabling the generation of individualized β‐secretase activity profiles.
Hyoyong Kim, Junseok Lee, Audrey Qian, You‐Ren Ji, Ryan Zhang, Qixin Hu, Christopher Kazu Williams, Han‐Yu Chuang, Matthew D. Smalley, Yaya Xu, Liang Gao, Mary C. Mayo, Ting Zhang, Edwin M. Posadas, Zaldy S. Tan, Harry V. Vinters, Keith Vossel, Shino Magaki, Yazhen Zhu, Hsian‐Rong Tseng   +19 more
wiley   +1 more source

Progression of deltamethrin resistance in Rhipicephalus microplus populations on communal farms of South Africa. [PDF]

Parasitol Res
Dzemo WD, Mavundela S.
europepmc   +1 more source

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Advanced Science, EarlyView.
The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A. Hoffmann, Jichao Fang, Rui Ji   +12 more
wiley   +1 more source

The replication rate of <i>Anaplasma marginale</i> is temperature-mediated in ticks. [PDF]

MicroPubl Biol
Devnath P, Noh SM, Jarvis SM, Earls K, Oyen KJ.   +4 more
europepmc   +1 more source