Results 201 to 210 of about 215,327 (355)
MOESM11 of Salivary gland proteome analysis of developing adult female Haemaphysalis longicornis ticks: molecular motor and TCA cycle-related proteins play an important role throughout development
, 2019 Shuguang Ren, Baowen Zhang, Xiaomin Xue, Xiaoshuang Wang, Huaqu Zhao, Xiaoli Zhang, Minjing Wang, Qi Xiao, Hui Wang, Jingze Liu +9 moreopenalex +1 more sourceHijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control
Advanced Science, EarlyView.Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang +21 morewiley +1 more sourceMolecular survey on tick-borne pathogens and Leishmania infantum in red foxes (Vulpes vulpes) from southern Italy
, 2021 Giovanni Sgroi, Roberta Iatta, Vincenzo Veneziano, Marcos Antônio Bezerra‐Santos, Paulina Maria Lesiczka, Kristýna Hrazdilová, Giada Annoscia, Nicola D’Alessio, Maryna Golovchenko, Nataliia Rudenko, David Modrý, Domenico Otranto +11 moreopenalex +2 more sourcesPotent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins
Advanced Science, EarlyView.Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang +16 morewiley +1 more sourceSMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer
Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang +16 morewiley +1 more sourceComprehensive validation of the rapid tick exposure test (RaTexT®): accuracy, reproducibility and comparative performance to detect acaricide resistance in livestock ticks. [PDF]
Parasit VectorsJongejan F, Berger L, Nagagi Y, Muhanguzi D, van der Heide M, Wiggers B, Elders L, de Avelar BR, Ferreira PT, Klafke GM. +9 moreeuropepmc +1 more source
