Blood feeding-induced transcriptomic changes in the hard tick <i>Ixodes persulcatus</i>. [PDF]
Lou Y +7 more
europepmc +1 more source
MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen +12 more
wiley +1 more source
Unlocking the Black Box: The Molecular Dialogue Between ASFV and Its Tick Host. [PDF]
Rodríguez-Mallon A, Lao González T.
europepmc +1 more source
We developed a macrophage‐based therapeutic platform, termed trackable tolerogenic macrophages (TTM), for dual‐function immunomodulation and visualization in vivo. TTM cells were engineered to overexpress PD‐L1, incorporate bioorthogonal cell surface tags, and load rapamycin for sustained release.
Yihui Wang +14 more
wiley +1 more source
Seasonality, Moisture, and Host Community Structure of Haemaphysalis Ticks in a Subtropical Urban Mosaic in Hong Kong, China. [PDF]
Seymour M, Wong K.
europepmc +1 more source
Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation
Targeting coacervates to the lysosome in the cytoplasm is a challenge. Here, we convert a tetrapeptide into lysosome‐targeting, membrane‐translocating coacervates. The lysosome‐sorting peptide coacervates facilitate coacervate‐mediated delivery of antibody antigen complexes and a PROTAC compound to the lysosome for the targeted degradation of cancer ...
Dingdong Yuan +7 more
wiley +1 more source
Bite by bite: Exposing hidden tick-borne disease risks among Nigeria's ruminant livestock workers. [PDF]
Daodu OB, Audu RA, Oluwayelu DO.
europepmc +1 more source
Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials
Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon +3 more
wiley +1 more source
Ectoparasite abundance and pathogen prevalence of the San Clemente Island fox (Urocyon littoralis clementae). [PDF]
Green DA +5 more
europepmc +1 more source

