Results 281 to 290 of about 291,682 (345)

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Metagenomic surveillance of tick-borne pathogens and microbiomes in Huntingdon County, Pennsylvania. [PDF]

One Health
Buonaccorsi A, McMullen BN, Builder B, Drummond K, Halteman S, See JC, Thomas E, Viands A, Worley S, Wright JR, Keeney J, Lamendella R.   +11 more
europepmc   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Global gene expression profiling of virulent and attenuated strains of Ehrlichia ruminantium: Toward the comprehension of pathogenesis [PDF]

, 2014
Emboule, Loïc, Gordon, Jonathan, Lebrigand, Kevin, Lefrançois, Thierry, Marcelino, Isabel, Mari, Bernard, Martinez, Dominique, Meyer, Damien, Pinarello, Valérie, Pruneau, Ludovic, Sheikboudou, Christian, Vachiery, Nathalie, Viari, Alain   +12 more
core  

Molecular detection of tick-borne pathogens in cattle ticks from the Lao People's Democratic Republic. [PDF]

Parasit Vectors
Nonthapa A, Rodpai R, Thanchomnang T, Boonroumkaew P, Sadaow L, Banouvong V, Laymanivong S, Thinnabut K, Tangkawanit U, Blair D, Intapan PM, Maleewong W, Sanpool O.   +12 more
europepmc   +1 more source

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

Advanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang, Zining Liu, Mengjun Li, Judun Zheng, Ruilin Zhang, Ke Liu, Xiaoxue Li, Shaoying Wen, Jingze Yu, Meijia Pan, Fengbo Ma, Kun Zhou, Zheng Zhao, Chenguang Shen, Yuhui Liao   +14 more
wiley   +1 more source

Differential alpha-gal expression during <i>Amblyomma hebraeum</i> and <i>Rhipicephalus evertsi</i> tick feeding and development: A driver for the development of alpha-gal syndrome in South Africa. [PDF]

J Allergy Clin Immunol Glob
Murangi T, Mans B, Pienaar R, Botha M, Facey-Thomas H, Cunningham S, Halajian A, Joshi L, Falcone FH, Horsnell W, Levin ME.   +10 more
europepmc   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Physiological diversity and temperature hardening in adult tick dermacentor variabilis (ACARI: IXODIDAE)

, 2006
Kai-Lun H. Hwang
openalex   +1 more source

Study on prevalence and identification of ticks in Humbo district, Southern Nations, Nationalities, and Peoples Region (SNNPR), Ethiopia

, 2013
Pawlos Wasihun, Derese Doda
openalex   +2 more sources