Results 311 to 320 of about 280,062 (388)

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Protocol for encapsulating ticks to study tick hematophagy and tick-virus-host interactions. [PDF]

STAR Protoc
Esteves E, Obellianne C, Thangamani S, Hermance ME.   +3 more
europepmc   +1 more source

diPaRIS: Dynamic and Interpretable Protein‐RNA Interactions Prediction With U‐Shaped Network and Novel Structure Encoding

Advanced Science, EarlyView.
This study presents diPaRIS, a deep learning method designed to predict dynamic protein‐ RNA interactions with enhanced accuracy. By integrating RNA structures in vivo through a novel encoding scheme for nucleotide correlations, diPaRIS improves the interpretability of binding motifs and outperforms current state‐of‐the‐art methods across multiple ...
Lishen Zhang, Chengqian Lu, Xiaoqing Peng, Fei Guo, Hongdong Li, Jianxin Wang   +5 more
wiley   +1 more source

Multilocus Sequence Typing Unveils Two Novel Genospecies of <i>Borrelia burgdorferi</i> Sensu Lato in Ticks Infesting Cricetid Rodents of Northern Chile. [PDF]

Transbound Emerg Dis
Parragué-Migone C, Santodomingo A, Thomas R, Muñoz-Leal S, Acosta-Jamett G.   +4 more
europepmc   +1 more source

SuFEx‐Enabled Catalytic Synthesis of Fluorescent Organosulfur Polymers for the Rapid Detection of Explosives

Advanced Science, EarlyView.
Rapid detection of explosives is essential for public safety and national security. Here, conjugated polymers (SPs), incorporating pentiptycene with organosulfur side chains, have been reported using sulfur(VI)‐fluoride exchange (SuFEx). The SP‐7 polymer exhibited exceptional fluorescence quenching (>99% in 60 s) for detecting nitroaromatic explosives.
Sun Bu Lee, Jaeyoung Heo, Seunghyun Noh, Tae Eun An, Gyeongsoo Kim, Gang Min Lee, Junggong Kim, Keunyoung Kim, Jongman Lee, Taeyeon Kim, Changsik Song, Han Yong Bae   +11 more
wiley   +1 more source

Ghosts of weather past? Impact of past and present weather-related factors on the seasonal questing activity of Ixodes ricinus nymphs in southwestern Finland. [PDF]

Parasit Vectors
Tanski N, Hänninen J, Kalliola R, Sormunen JJ.   +3 more
europepmc   +1 more source

Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis

Advanced Science, EarlyView.
Fumadó Navarro et al. present an optimized strategy to generate vascular‐like networks that infiltrate within cerebral organoids with promising signs of blood‐brain barrier characteristics, preserved stiffness, uniform morphology, enhanced media diffusion, and reduced necrotic core.
Josep Fumadó Navarro, Siobhan Crilly, Wai Kit Chan, Shane Browne, John O. Mason, Catalina Vallejo‐Giraldo, Abhay Pandit, Mihai Lomora   +7 more
wiley   +1 more source

Molecular Surveillance of <i>Neoehrlichia mikurensis</i> and <i>Anaplasma phagocytophilum</i> in Ticks from Urbanized Areas of Lithuania. [PDF]

Pathogens
Snegiriovaitė J, Lipatova I, Razgūnaitė M, Paulauskas A, Radzijevskaja J.   +4 more
europepmc   +1 more source

Lone Star Tick, Amblyomma Americanum [PDF]

, 1957
Lancaster, J. L.
core   +2 more sources

New Strategy for Cluster‐Based Covalent Organic Framework: Thermally Induced Covalent Crosslinking of Highly Stable Copper Clusters

Advanced Science, EarlyView.
A thermally induced covalent crosslinking strategy is used to accelerate the photogenerated carrier transport of cluster‐based photocatalysts, the covalent crosslinking between clusters accelerates the dynamic transfer of photoexcited charge carriers, increases the light utilization ability, and favors CO2 adsorption as well as *COOH generation, which ...
Jian‐Peng Dong, Yue Xu, Ling Yao, Le Wang, Gang Li, Rui Wang, Shuang‐Quan Zang   +6 more
wiley   +1 more source