Results 31 to 40 of about 48,508 (266)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Isolation of Small Number of Cryptosporidium parvum Oocyst Using Immunochromatography
Iranian Journal of Parasitology, 2014 Background: Cryptosporidium parvum causes severe gastroenteritis in immunocompromised human and new borne animals. The organism can be transmitted through water. Since small number of C. parvum is infectious, the aim of the present study was to develop a
Elahe Ebrahimzade +4 more
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MicroorganismsTick-borne rickettsioses are considered among the oldest known vector-borne zoonotic diseases. Among the rickettsiae, Rickettsia africae is the most reported and important in Africa, as it is the aetiological agent of African tick bite fever (ATBF ...
Andeliza Smit +11 more
doaj +1 more source
Comparative microbiomes of ticks collected from a black rhino and its surrounding environment
International Journal for Parasitology: Parasites and Wildlife, 2019 ‘Eliska,’ an endangered black rhino (Diceros bicornis), died suddenly in Mkomazi National Park in Tanzania in 2016. Three Amblyomma gemma ticks were collected from Eliska's body, and four ticks were collected from the surrounding field.
Seogwon Lee +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Molecular detection of Anaplasma phagocytophilum in carrier cattle of Iran - first documented report
Iranian Journal of Microbiology, 2009 Background and Objectives: Anaplasma phagocytophilum is a zoonotic, tick borne rickettsial pathogen. A. phagocytophilum has been detected in North America, Europe, Africa and Asia by molecular methods.
V Noaman, P Shayan
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Emerging Infectious Diseases, 2015 Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in East Asia caused by SFTS virus (SFTSV), a newly discovered phlebovirus. The Haemaphysalis longicornis tick has been suspected to be the vector of SFTSV.
Li-Mei Luo +11 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Molecular Study of Sheep Malignant Theileriosis at Barka Region in the Sultanate of Oman
Iranian Journal of Parasitology, 2011 Background: We used the PCR technique based on the abovementioned primer pair and sequencing to demonstrate the Theileria infection in the sheep samples collected from Sultanate of Oman.
P Shayan +4 more
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