Results 71 to 80 of about 215,327 (355)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Molecular screening of tick-borne pathogens in host-seeking Haemaphysalis punctata Canestrini & Fanzago, 1878 (Ixodoidea: Ixodidae) in Anatolia with the first report of Burana virus

Parasites & Vectors
Background Haemaphysalis punctata is a widespread Palearctic tick species, yet its role in the circulation of tick-borne pathogens in Türkiye remains poorly characterized.
Ömer Orkun, Tuğba Özdemir, Maide Nur Gündoğdu, Mesut Yiğit, Ahmet Deniz, Zati Vatansever   +5 more
doaj   +1 more source

Prevalence of Borrelia burgdorferi in ticks removed from skin of people and circumstances of being bitten – research from the area of Poland, 2012–2014

Annals of Agricultural and Environmental Medicine, 2018
Introduction During feeding, the tick sucks blood from the host along with the pathogens that are in the blood, simultaneously exchanging its own pathogens with the host. Humans can also be a host.
Edyta Gałęziowska, Jolanta Rzymowska, Nella Najda, Przemysław Kołodziej, Renata Domżał- Drzewicka, Marcin Rząca, Bożena Muraczyńska, Marianna Charzyńska- Gula, Zdzisława Szadowska- Szlachetka, Barbara Ślusarska, Edyta Guty   +10 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Distribution of Tick Vectors of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Collected from Four Environments in Jeju

Korean Journal of Clinical Laboratory Science, 2020
The distribution of ticks and severe fever with thrombocytopenia syndrome virus (SFTSV) pathogens were investigated by collecting ticks from March to November 2018 in four environments (grass fields, copses, mountain roads, and tombs) in Jeju.
Kyoung A Chung, Hyeon Je Song, Hyeok Jae Lee, Chul Park, Min Yeung Seo   +4 more
doaj   +1 more source

Spatial and temporal patterns of the emerging tick-borne pathogen Borrelia miyamotoi in blacklegged ticks (Ixodes scapularis) in New York

Parasites & Vectors, 2021
Borrelia miyamotoi, a bacterium that causes relapsing fever, is found in ixodid ticks throughout the northern hemisphere. The first cases of human infection with B. miyamotoi were identified in 2011.
F. Keesing, D. J. McHenry, M. H. Hersh, R. S. Ostfeld   +3 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Molecular Study of Sheep Malignant Theileriosis at Barka Region in the Sultanate of Oman

Iranian Journal of Parasitology, 2011
Background: We used the PCR technique based on the abovementioned primer pair and sequenc­ing to demonstrate the Theileria infection in the sheep samples collected from Sultanate of Oman.
P Shayan, E Ebrahimzadeh, MH Tageldin, N Amininia, B Eckert   +4 more
doaj  

DYNAMICS OF TICKS’ INFESTATION WITH BORRELIA GENUS BACTERIA AND TICK-BORNE ENCEPHALITIS VIRUS IN KIROV REGION

Инфекция и иммунитет, 2017
Tick-borne encephalitis and tick-borne borreliosis (or Lyme disease) are one of the most known and the most spread transmissible diseases of human. Nowadays it was proved that these diseases are diagnosed among domestic animals as well. Ixodida ticks are
E. A. Bessolitsyna, S. A. Volkov, F. S. Stolbova   +2 more
doaj   +1 more source

Role of three tick species in the maintenance and transmission of Severe Fever with Thrombocytopenia Syndrome Virus.

PLoS Neglected Tropical Diseases, 2020
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel phlebovirus in the Bunyaviridae family, causing SFTS with high mortality rate. Haemaphysalis longicornis ticks has been demonstrated as a competent vector of SFTSV by experimental ...
Yuan-Yuan Hu, Lu Zhuang, Kun Liu, Yi Sun, Ke Dai, Xiao-Ai Zhang, Pan-He Zhang, Zhi-Chun Feng, Hao Li, Wei Liu   +9 more
doaj   +1 more source