Results 11 to 20 of about 1,363 (130)

Brain and cognitive correlates of social status across race/ethnicity and sex/gender. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Subjective social status (SSS) in the United States relates to cognition. Few studies assess SSS in one's community, examine brain correlates, or consider associations across the intersection of sex/gender and race/ethnicity. METHODS A total of 867 participants from the Washington Heights‐Inwood Columbia Aging Project completed ...
Scambray KA, Walters ME, Morris EP, Pierce RM, Brickman AM, Zahodne LB.   +5 more
europepmc   +2 more sources

Cholinergic basal forebrain atrophy in Parkinson's disease with freezing of gait. [PDF]

Ann Clin Transl Neurol, 2023
Abstract Background Mounting research support that cholinergic dysfunction plays a prominent role in freezing of gait (FOG), which commonly occurs in Parkinson's disease (PD). Basal forebrain (BF), especially the cholinergic nuclei 4 (Ch4), provides the primary source of the brain cholinergic input.
Gan C, Cao X, Wang L, Sun H, Ji M, Zhang H, Yuan Y, Zhang K.   +7 more
europepmc   +2 more sources

Microstructural Characterization of Short Association Fibers Related to Long-Range White Matter Tracts in Normative Development. [PDF]

Hum Brain Mapp
This study investigates superficial white matter using advanced quantitative diffusion tractography. This paper addresses three key objectives: (1) mapping short association fibers in relation to long‐range white matter tracts, (2) characterizing typical neurodevelopmental changes, and (3) investigating the relationship between microstructural changes ...
Cho C, Chamberland M, Rheault F, Moyer D, Landman BA, Schilling KG.   +5 more
europepmc   +2 more sources

Tau mediates the impact of amyloid and vascular disease burden on the trajectory of clinical symptoms. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Amyloid (A) and vascular (V) pathologies often co‐occur and progress over decades. We leveraged chronicity, defined as the years above a biomarker‐positivity threshold, to examine how the timing of A and V relates to cognitive decline.
Du L, Langhough RE, Hermann BP, Jonaitis EM, Betthauser TJ, Rivera-Rivera LA, Cody KA, Chin NA, Cadman RV, Johnson KM, Field AS, Asthana S, Eisenmenger L, Christian BT, Johnson SC.   +14 more
europepmc   +2 more sources

Shape Alterations of Subcortical Nuclei Correlate With Amyotrophic Lateral Sclerosis Progression. [PDF]

Brain Behav
Extensive shape alterations of subcortical nuclei noted in amyotrophic lateral sclerosis (ALS) patients with fast progression implicated subcortical shape being a potential neuroimaging biomarker for ALS progression, facilitating early diagnosis and prompt management of patients with ALS.
Yuan Y, Fu Y, Wang X, Hu F, Zhao Q, He C, Tang L, Li Y, Bu Y, Song X, Liu Q, Liu Z, Xu R, Cao W, Zhang Y, Yi X, Wang J, Chen BT.   +17 more
europepmc   +2 more sources

Neuroimaging correlates and biomarker performance of a fully automated plasma p-tau217/Aβ42 ratio assay in a clinical cohort with Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Blood‐based biomarkers offer scalable, non‐invasive tools for Alzheimer's disease (AD) detection. We investigated the performance of plasma biomarkers associated with AD on the automated Beckman Coulter Access DxI 9000 analyzer. METHODS This cross‐sectional study included 262 individuals from across the AD continuum.
Um YH, Wynveen P, Holland M, Bhatt K, Vucetic Z, Engel B, Carlson C, Becker A, Meier IB, Narayan VA, Wang SM, Kang DW, Kim S, Kim S, Kim D, Choe YS, Kim REY, Ha S, Lim HK.   +18 more
europepmc   +2 more sources

Spatiotemporal profile of atrophy in the first year following moderate‐severe traumatic brain injury

Human Brain Mapping, Volume 44, Issue 13, Page 4692-4709, September 2023., 2023
Traumatic brain injury (TBI) triggers progressive neurodegeneration resulting in brain atrophy that continues months‐to‐years following injury. Our findings demonstrate msTBI results in characteristic progressive neurodegeneration patterns that are divergent across regions and scale with the severity of injury.
Daniel J. Brennan, Jeffrey Duda, Jeffrey B. Ware, John Whyte, Joon Yul Choi, James Gugger, Kristen Focht, Alexa E. Walter, Tamara Bushnik, James C. Gee, Ramon Diaz‐Arrastia, Junghoon J. Kim   +11 more
wiley   +1 more source

Improving Accuracy of Brainstem MRI Volumetry: Effects of Age and Sex, and Normalization Strategies

Frontiers in Neuroscience, 2020
Background: Brainstem-mediated functions are impaired in neurodegenerative diseases and aging. Atrophy can be visualized by MRI. This study investigates extrinsic sources of brainstem volume variability, intrinsic sources of anatomical variability, and ...
Laura Sander, Laura Sander, Antal Horvath, Simon Pezold, Simon Andermatt, Michael Amann, Tim Sinnecker, Tim Sinnecker, Tim Sinnecker, Maria J. Wendebourg, Maria J. Wendebourg, Eva Kesenheimer, Eva Kesenheimer, Özgür Yaldizli, Özgür Yaldizli, Ludwig Kappos, Ludwig Kappos, Cristina Granziera, Cristina Granziera, Jens Wuerfel, Philippe Cattin, Regina Schlaeger, Regina Schlaeger   +22 more
doaj   +1 more source

Distinct patterns of neurodegeneration after TBI and in Alzheimer's disease

Alzheimer's &Dementia, Volume 19, Issue 7, Page 3065-3077, July 2023., 2023
Abstract Introduction Traumatic brain injury (TBI) is a dementia risk factor, with Alzheimer's disease (AD) more common following injury. Patterns of neurodegeneration produced by TBI can be compared to AD and aging using volumetric MRI. Methods A total of 55 patients after moderate to severe TBI (median age 40), 45 with AD (median age 69), and 61 ...
Neil S.N. Graham, James H. Cole, Niall J. Bourke, Jonathan M. Schott, David J. Sharp   +4 more
wiley   +1 more source

Deteksi Molekuler Penyebab Penyakit Kuning (Tomato Chlorosis Virus dan Tomato Infectious Chlorosis Virus) pada Tanaman Tomat [PDF]

, 2015
This research was aimed to detect the ToCV and TICV caused yellowing disease on tomatoes by molecular detection. Leaf samples of symptomatic plants were taken from Ketep (Magelang), then the leaves were identified by reverse transcription-polymerase ...
Fajarfika, R. (Resti), Hartono, S. (Sedyo), Somowiyarjo, S. (Susamto), Sulandari, S. (Sri)   +3 more
core   +2 more sources