Results 131 to 140 of about 212,997 (211)
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT Propylthiouracil (PTU) is a thioamide drug used in the management of hyperthyroidism in selected clinical settings. While PTU is associated with well‐known adverse effects such as hepatotoxicity, agranulocytosis, and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, ototoxicity is an exceptionally rare complication.
Adane Alemayehu Abera +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1389-1401, November 2026.A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Divakar Budda +2 more
wiley +1 more source
, 2019 TID hash joins are a simple and memory-efficient method for processing large join queries. They are based on standard hash join algorithms but only store TID/key pairs in the hash table instead of entire tuples. This typically reduces memory requirements
Rahm, Erhard, Marek, Robert
core
MedComm, Volume 7, Issue 11, November 2026.ABSTRACT This retrospective study was designed to evaluate the safety and efficacy of adding a thalidomide‐based cocktail (the TCC cocktail—comprising thalidomide, carmofur, and compound mylabris capsule) to transarterial chemoembolization (TACE) for unresectable hepatocellular carcinoma (HCC) in real‐world practice.
Jinzhi Xu +17 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Space Weather, Volume 24, Issue 11, November 2026.Abstract During November 2025 thousands of commercial aircraft (Airbus A320s) had to be grounded due to the risk of ionizing radiation effects on the avionics system. Safety‐critical systems continue to use modern commercial devices, and therefore an understanding of their responses within enhanced radiation environments is crucial to ensure reliable ...
M. Barker, K. Ryden, C. Dyer, F. Lei
wiley +1 more source
Treprostinil: Mechanism of Action, Clinical, and Translational Science
Clinical and Translational Science, Volume 19, Issue 11, November 2026.ABSTRACT Treprostinil is a synthetic prostacyclin analogue with a tricyclic benzindene structure that confers markedly enhanced metabolic stability relative to native prostacyclin, enabling delivery by four distinct routes—intravenous, subcutaneous, inhaled, and oral—that together constitute a mainstay of pharmacotherapy for pulmonary arterial ...
Muhammad Sameed +2 more
wiley +1 more source
Equine Veterinary Education, Volume 38, Issue 11, Page e837-e845, November 2026.Summary A 26‐year‐old pony mare was referred for weight loss, dysphagia, lethargy and fever. Clinical examination revealed left temporal swelling, masseter muscle atrophy and malocclusion. Computed tomography examination showed severe temporomandibular joint (TMJ) alteration, extensive osteolysis of the mandibular condyle and temporal bone and ...
L. Gross +3 more
wiley +1 more source
Veterinary Ophthalmology, Volume 29, Issue 6, November 2026.ABSTRACT Purpose To describe cases of canine idiopathic periocular granulomatous inflammation. Material and Methods Clinical records were reviewed. Animal Studied At the time of presentation, the four patients (German Shepherd dog, mixed breed, Magyar Vizsla, Hovawart) were 1.5–5 (mean 3.75) years old. All dogs were female; two were spayed.
J. Kurwinkel +5 more
wiley +1 more source
Geophysical Research Letters, Volume 53, Issue 20, 28 October 2026.Abstract We present the first coordinated study of nighttime mesosphere‐ionosphere coupling over the continental United States (CONUS) from January through November 2024 using NASA Atmospheric Waves Experiment (AWE) airglow measurements near 87 km and GNSS Total Electron Content observations near 300 km.
Sreelekshmi Radhakrishnan Girijakumary +1 more
wiley +1 more source