Results 31 to 40 of about 8,892 (260)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Application of Airborne LiDAR Measurements to the Topographic Survey of the Tidal Flats of the Northern Jiangsu Radial Sand Ridges in the Southern Yellow Sea

Frontiers in Marine Science, 2022
The northern Jiangsu radial sand ridges are typical geomorphic deposit units distributed off the Jiangsu coast. A coastal tidal flat typically develops and provides a good habitat for many migratory birds and benthic organisms.
Haifeng Zhang, Haifeng Zhang, Lian Wang, Yifei Zhao, Jicheng Cao, Min Xu   +5 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

Advanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao, Jiaojiao Zhang, Shideng Yuan, Xinmeng Yu, Keming Wan, Xiaoguang Duan, Zhining Wang   +6 more
wiley   +1 more source

Insights into the Genetic Connectivity and Climate-Driven Northward Range Expansion of Turbo sazae (Gastropoda: Turbinidae) Along the Eastern Coast of Korea

Animals
Turbo sazae, a commercially and ecologically significant marine gastropod traditionally found in Jeju Island and the southern coast of Korea, is experiencing a reported northward expansion into the East Sea, likely influenced by rising seawater ...
Young-Ghan Cho, Kyungman Kwon, Hyun Soo Rho, Won-Gi Min, Hee-Do Jeung, Un-Ki Hwang, Yong-Kyun Ryu, Areumi Park, Hyun-Ki Hong, Jong-Seop Shin, Hyun-Sung Yang   +10 more
doaj   +1 more source

Effects of sea level rise and tidal flat growth on tidal dynamics and geometry of the Elbe estuary [PDF]

Ocean Science
Future global mean sea level rise (SLR) will affect coastlines and estuaries in the North Sea and therefore also coastal protection structures, unique local ecosystems and important waterways. SLR will not only raise water levels but also influence tidal
T. F. Mahavadi, R. Seiffert, J. Kelln, P. Fröhle   +3 more
doaj   +1 more source

Retrieval of Tidal Flat Elevation Based on Remotely Sensed Moisture Approach

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
Due to challenging conditions of field survey techniques, it is difficult to measure the topography of tidal flats, an important parameter to understanding the evolution and dynamics of the constantly changing zone.
Huan Li, Mark Cutler, Dong Zhang, Samuel Daramola, Yaquan Zhu, Zheng Gong   +5 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Impact of Increased Satellite Observation Frequency on Mapping of Long-Term Tidal Flat Area Changes

Remote Sensing
Remote sensing of tidal flats and their dynamic changes is essential for understanding and conserving intertidal ecosystems. As a highly dynamic land cover type influenced by tidal variations, tidal flats present challenges for consistent long-term ...
Jinqing Wang, Xiao Zhang, Tingting Zhao, Liangyun Liu   +3 more
doaj   +1 more source