Results 51 to 60 of about 212,541 (290)

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang   +12 more
wiley   +1 more source

The Conceptual Design of a Tidal Power Plant in Taiwan

open access: yesJournal of Marine Science and Engineering, 2014
Located on the northwestern of Taiwan, the Matsu archipelago is near mainland China and comprises four islands: Nangan, Beigan, Juguang, and Dongyin. The population of Matsu totals 11,196 and is chiefly concentrated on Nangan and Beigan.
Jia-Shiuan Tsai, Falin Chen
doaj   +1 more source

Mathematical analysis of the turbine coefficient of performance for tidal stream turbines [PDF]

open access: yes, 2014
Unregulated water currents such as tides and ocean currents include energy that could be utilized for electricity production. These currents can be seen as dead bodies of water with potential energy, driven by gravity or alive moving with a kinetic ...
Abdel Aleem, SHE, Ibrahim, AM, Zobaa, AF
core  

Discovery of tidal tails around the distant globular cluster Palomar 14 [PDF]

open access: yes, 2010
We report the detection of a pair of degree-long tidal tails associated with the globular cluster Palomar 14, using images obtained at the CFHT. We reveal a power-law departure from a King profile at large distances to the cluster center. The density map
A. Sollima   +44 more
core   +5 more sources

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

open access: yesAdvanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng   +13 more
wiley   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Can Tidal Current Energy Provide Base Load?

open access: yesEnergies, 2013
Tidal energy belongs to the class of intermittent but predictable renewable energy sources. In this paper, we consider a compact set of geographically diverse locations, which have been assessed to have significant tidal stream energy, and attempt to ...
Simone Giorgi, John V. Ringwood
doaj   +1 more source

Power Spectra for Galaxy Shape Correlations [PDF]

open access: yes, 2001
It has recently been argued that the observed ellipticities of galaxies may be determined at least in part by the primordial tidal gravitational field in which the galaxy formed.
Mackey, Jonathan
core   +4 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Output characteristics of tidal current power stations [PDF]

open access: yes, 2004
With increasing targets being set for renewable-derived electricity generation, wind power is currently the preferred technology. It is widely accepted that due to the stochastic nature of wind, there is an upper limit to the capacity that can be ...
Clarke, Joseph Andrew   +2 more
core  

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