Results 61 to 70 of about 305,276 (277)

ARDS: hidden perils of an overburdened diagnosis

open access: yesCritical Care, 2022
A diagnosis of ARDS serves as a pretext for several perilous clinical practices. Clinical trials demonstrated that tidal volume 12 ml/kg increases patient mortality, but 6 ml/kg has not proven superior to 11 ml/kg or anything in between.
Martin J. Tobin
doaj   +1 more source

Variability of Tidal Volume in Patient-Triggered Mechanical Ventilation in ARDS [PDF]

open access: yesRespiratory Care, 2017
BACKGROUND: Limiting tidal volume (V T ) in patients with ARDS may not be achieved once patient-triggered breaths occur. Furthermore, ICU ventilators offer numerous patient-triggered modes that work differently across brands.
Sophie, Perinel-Ragey   +2 more
openaire   +2 more sources

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

open access: yesAdvanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang   +13 more
wiley   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

open access: yesAdvanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo   +7 more
wiley   +1 more source

Formation of offshore tidal sand banks triggered by a gasmined bed subsidence [PDF]

open access: yesContinental Shelf Research, 2002
Offshore gasmining is an example of a human intervention with a morphological impact. On land, it is usually attended with a dish-like bed depression. We show that, if located at sea, such a bed depression can become morphodynamically active by triggering mechanisms related to tidal sand bank formation.
Roos, Pieter C.   +1 more
openaire   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice

open access: yesScientific Reports, 2021
The roles of endothelial nitric oxide synthase (eNOS) in the ventilatory responses during and after a hypercapnic gas challenge (HCC, 5% CO2, 21% O2, 74% N2) were assessed in freely-moving female and male wild-type (WT) C57BL6 mice and eNOS knock-out ...
Paulina M. Getsy   +6 more
doaj   +1 more source

FSI analysis of deformation along offshore pile structure for tidal current power [PDF]

open access: yes, 2013
Due to global warming, the need to secure an alternative clean energy resource has become an international issue. Tidal current power is now recognized as one of the clean power resources in Korea, where there are many strong current regions on the west ...
Rho, Yu-Ho   +4 more
core   +4 more sources

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

open access: yesAdvanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen   +12 more
wiley   +1 more source

Unmasking malignant hyperthermia: a rapid response to a hypermetabolic crisis: case report

open access: yesFrontiers in Anesthesiology
IntroductionMalignant Hyperthermia is a rare, life-threatening pharmacogenetic disorder that can occur after exposure to triggering anesthetic agents, including volatile anesthetics and succinylcholine.Case presentationAn 18-year-old male with multiple ...
En Chang   +5 more
doaj   +1 more source

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