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Evaluation of Plasma Biomarkers to Understand the Biology and Heterogeneity of Treatment Effect in Lower Tidal Volume Ventilation Facilitated by Extracorporeal CO2 Removal in Acute Hypoxemic Respiratory Failure: A Secondary Analysis of the REST Trial. [PDF]
Crit Care ExplorBoyle AJ +18 more
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Erratum: Feasibility of Setting the Tidal Volume Based on End-Expiratory Lung Volume: A Pilot Clinical Study: Erratum. [PDF]
Crit Care Exploreuropepmc +1 more source
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Ventilation with Small Tidal Volumes
New England Journal of Medicine, 2002Human survival depends on the exchange of fresh air with carbon dioxide in the blood. Since this exchange takes place in the alveoli, one of the first concepts taught in respiratory physiology is t...
Arthur S, Slutsky, Jeffrey M, Drazen
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Chest, 1990
High airway pressure may be injurious to lung parenchyma, but lowering airway pressure using conventional mechanical ventilation necessitates lowering tidal volume (VT). Intubated patients in the surgical intensive care unit (SICU) were randomly assigned to group 1 (VT = 12 ml/kg, n = 56) or group 2 (VT = 6 ml/kg, n = 47).
P C, Lee +3 more
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High airway pressure may be injurious to lung parenchyma, but lowering airway pressure using conventional mechanical ventilation necessitates lowering tidal volume (VT). Intubated patients in the surgical intensive care unit (SICU) were randomly assigned to group 1 (VT = 12 ml/kg, n = 56) or group 2 (VT = 6 ml/kg, n = 47).
P C, Lee +3 more
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Journal of Applied Physiology, 1979
In progressive exercise increased tidal volume (VT) accompanies increased ventilation (VE) until a VT plateau is reached. We observed in 13 subjects a correspondence between the arrival of the VT plateau and the anaerobic threshold (AT). To examine this association between a mechanical event (the VT plateau) and a metabolic event (the AT), we changed ...
B J, Martin, J V, Weil
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In progressive exercise increased tidal volume (VT) accompanies increased ventilation (VE) until a VT plateau is reached. We observed in 13 subjects a correspondence between the arrival of the VT plateau and the anaerobic threshold (AT). To examine this association between a mechanical event (the VT plateau) and a metabolic event (the AT), we changed ...
B J, Martin, J V, Weil
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JAMA: The Journal of the American Medical Association, 1973
To the Editor.— In the 19th century, cannabis products were commonly used in the treatment of asthma. 1-3 Smoking marihuana, on the other hand, is associated with bronchitis and other deleterious effects on lung function. 4 The present report deals with acute marihuana effects on pulmonary capacity in nonasthmatic regular marihuana smokers. Method.—
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To the Editor.— In the 19th century, cannabis products were commonly used in the treatment of asthma. 1-3 Smoking marihuana, on the other hand, is associated with bronchitis and other deleterious effects on lung function. 4 The present report deals with acute marihuana effects on pulmonary capacity in nonasthmatic regular marihuana smokers. Method.—
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JAMA, 2012
lunginjurydevelopment(RR,0.33;95%CI,0.23-0.47),pulmonary infection (RR, 0.45; 95% CI, 0.22-0.92), and mortality (RR, 0.64; 95% CI, 0.46-0.89). Although these data seem compelling, several factors must be considered in their interpretation. A total of 15 randomized controlled trials were combined with 5 observational studies, but the observational ...
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lunginjurydevelopment(RR,0.33;95%CI,0.23-0.47),pulmonary infection (RR, 0.45; 95% CI, 0.22-0.92), and mortality (RR, 0.64; 95% CI, 0.46-0.89). Although these data seem compelling, several factors must be considered in their interpretation. A total of 15 randomized controlled trials were combined with 5 observational studies, but the observational ...
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Quick reference tidal volume cards reduce the incidence of large tidal volumes during surgery
Journal of Anesthesia, 2017Ventilation with large tidal volumes (V T), greater than 10 ml/kg of predicted body weight (PBW), is associated with worse outcomes in critically ill and surgical patients. We hypothesized that the availability of quick reference cards with proposed V T ranges specific to gender and different heights would reduce the intraoperative use of large V T ...
Chirag K. Shah +4 more
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