Results 41 to 50 of about 3,327,676 (338)

Promoting Evidence-Based Practice in Acute Respiratory Distress Syndrome: A Systematic Review

Critical Care Explorations, 2021
OBJECTIVE:. Low tidal volume ventilation and prone positioning are recommended therapies yet underused in acute respiratory distress syndrome. We aimed to assess the role of interventions focused on implementation of low tidal volume ventilation and ...
Shewit P. Giovanni, MD, MS, Ann L. Jennerich, MD, MS, ATSF, Tessa L. Steel, MD, MPH, Sharukh Lokhandwala, MD, MS, Waleed Alhazzani, MBBS, MS, FRCPC, Curtis H. Weiss, MD, MS, Catherine L. Hough, MD, MS   +6 more
doaj   +1 more source

Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS

Critical Care, 2019
Background In patients with acute respiratory distress syndrome (ARDS), low tidal volume ventilation has been associated with reduced mortality. Driving pressure (tidal volume normalized to respiratory system compliance) may be an even stronger predictor
Michael J. Lanspa, Ithan D. Peltan, Jason R. Jacobs, Jeffrey S. Sorensen, Lori Carpenter, Jeffrey P. Ferraro, Samuel M. Brown, Jay G. Berry, Raj Srivastava, Colin K. Grissom   +9 more
doaj   +1 more source

Extraction and Analysis of Respiratory Motion Using a Comprehensive Wearable Health Monitoring System

Sensors, 2021
Respiratory activity is an important vital sign of life that can indicate health status. Diseases such as bronchitis, emphysema, pneumonia and coronavirus cause respiratory disorders that affect the respiratory systems.
Uduak Z. George, Kee S. Moon, Sung Q. Lee   +2 more
doaj   +1 more source

High flow nasal cannula and low level continuous positive airway pressure have different physiological effects during de novo acute hypoxemic respiratory failure

Annals of Intensive Care
Background Large tidal volumes during de novo acute hypoxemic respiratory failure (AHRF) may promote patient self-inflicted lung injury. Tidal volume assessment under high flow nasal cannula (HFNC) is not routinely feasible at the bedside.
Samuel Tuffet, Mohamed Ahmed Boujelben, Anne-Fleur Haudebourg, Tommaso Maraffi, François Perier, Pascale Labedade, Elsa Moncomble, Ségolène Gendreau, Matthieu Lacheny, Emmanuel Vivier, Armand Mekontso-Dessap, Guillaume Carteaux   +11 more
doaj   +1 more source

Validation of a tool for estimating clinician recognition of ARDS using data from the international LUNG SAFE study.

PLOS Digital Health, 2023
Under-recognition of acute respiratory distress syndrome (ARDS) by clinicians is an important barrier to adoption of evidence-based practices such as low tidal volume ventilation. The burden created by the COVID-19 pandemic makes it even more critical to
Meagan A Bechel, Fabiana Madotto, Adam R Pah, Giacomo Bellani, John G Laffey, Tài Pham, Luís A Nunes Amaral, Curtis H Weiss   +7 more
doaj   +1 more source

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao, Hongliang Ge, Chenchao Lin, Xiyue Wu, Jianwu Chen   +4 more
wiley   +1 more source

Correlation of BMI Variation with Tidal Function in Healthy Young Adults

Journal of Islamic International Medical College, 2021
Objective: To observe the effect of Body Mass Index (BMI) on Tidal volume and its rate of air flow in healthy young adults. Study Design: Cross-sectional study Place and Duration of Study: Department of Physiology at Shalamar Medical and Dental College ...
Ayesha Sadiqa, Farida Munawar
doaj  

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

Does tidal volume challenge improve the feasibility of pulse pressure variation in patients mechanically ventilated at low tidal volumes? A systematic review and meta-analysis

Critical Care, 2023
Background Pulse pressure variation (PPV) has been widely used in hemodynamic assessment. Nevertheless, PPV is limited in low tidal volume ventilation. We conducted this systematic review and meta-analysis to evaluate whether the tidal volume challenge ...
Xiaoying Wang, Shuai Liu, Ju Gao, Yang Zhang, Tianfeng Huang   +4 more
doaj   +1 more source

Tidal volume in acute respiratory distress syndrome: how best to select it.

Annals of Translational Medicine, 2017
Mechanical ventilation is the type of organ support most widely provided in the intensive care unit. However, this form of support does not constitute a cure for acute respiratory distress syndrome (ARDS), as it mainly works by buying time for the lungs ...
M. Umbrello, A. Marino, D. Chiumello
semanticscholar   +1 more source