Results 41 to 50 of about 261,587 (300)

Lateral Marsh Edge Erosion as a Source of Sediments for Vertical Marsh Accretion [PDF]

, 2018
With sea level rise accelerating and sediment inputs to the coast declining worldwide, there is concern that tidal wetlands will drown. To better understand this concern, sources of sediment contributing to marsh elevation gain were computed for Plum ...
Barbier, Bauer, Blum, Blum, Cahoon, Cavatorta, Claessens, Cook, Costanza, Day, Day, Dhillon, Donnelly, Donnelly, Engelhart, Eyre, Fagherazzi, Fagherazzi, Foley, Forbrich, French, Ganju, Ganju, Geyer, Gittman, Gosselink, Hayden, Hein, Hobbs, Hopkinson, Hughes, Kirwan, Kirwan, Kirwan, Koch, Lane, Leonardi, Leonardi, Leonardi, Levin, Magirl, Marcus, Mariotti, Mariotti, Mariotti, Mattheus, McGeehin, McKee, Meade, Meade, Megonigal, Millette, Milliman, Mineau, Morris, Morris, Morris, Morris, Morris, Mudd, Pasternack, Pavich, Priestas, Rahmstorf, Raymond, Redfield, Redfield, Redfield, Reed, Rovere, Schmidt, Schwimmer, Sholkovitz, Stuiver, Swales, Syvitski, Townsend, Trimble, Vallino, Vallino, Walsh, Warrick, Warrick, Watson, Weston, Wilson, Wollheim, Wollheim, Worm, Yarbro, Zhao   +90 more
core   +3 more sources

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Stability, chaos and entrapment of stars in very wide pairs

, 2011
The relative motion of stars and other celestial objects in very wide pairs, separated by distances of the order of 1 pc, is strongly influenced by the tidal gravitational potential of the Galaxy.
Anosova, Astakhov, Beech, Beech, Bertolami, Caballero, Chambers, Fukushige, Hayes, Hayes, Hénon, Jiang, King, Kouwenhoven, Makarov, Makarov, Makarov, Milgrom, Shaya, Valeri V. Makarov, Wertheimer   +20 more
core   +1 more source

Best PEEP trials are dependent on tidal volume [PDF]

Critical Care, 2018
Determining the optimal positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome remains an area of active investigation. Most trials individualizing PEEP optimize one physiologic parameter (e.g., driving pressure) by titrating PEEP while holding other ventilator settings constant.
Todd W. Rice, Andrew C. McKown, Matthew W. Semler   +2 more
openaire   +4 more sources

Comprehensive Characterization of the Immune Microenvironment Based on Nested Resampling Machine Learning Framework Identifies TRAF3 Interacting Protein 3 as a Promising Regulator to Improve the Resistance to Immunotherapy in Glioma

Advanced Science, EarlyView.
This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang, Fei Wang, Yulian Zhang, Run Huang, Chuanpeng Zhang, Lu Zhao, Hanhan Dang, Xinyu Tao, Yue Lu, Dengfeng Lu, Yunsheng Zhang, Kun He, Jiancong Weng, Zhouqing Chen, Zhong Wang, Yanbing Yu   +15 more
wiley   +1 more source

Patterns of recruitment and injury in a heterogeneous airway network model [PDF]

, 2015
In respiratory distress, lung airways become flooded with liquid and may collapse due to surface-tension forces acting on air-liquid interfaces, inhibiting gas exchange.
Cressoni M, Murphy SL, Oliver E. Jensen, Peter S. Stewart, The Acute Respiratory Distress Syndrome Network, Weibel ER   +5 more
core   +1 more source

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

A systematic numerical study of the tidal instability in a rotating triaxial ellipsoid [PDF]

, 2010
The full non-linear evolution of the tidal instability is studied numerically in an ellipsoidal fluid domain relevant for planetary cores applications.
Aldridge, Bayly, Benton, Boubnov, Chan, Craik, D. Cébron, Eloy, Eloy, Gledzer, Gledzer, Gledzer, Greenspan, Haj-Hariri, Herreman, Hollerbach, Hough, J. Leontini, Kelvin, Kerswell, Kerswell, Kerswell, Lacaze, Lacaze, Lacaze, Lacaze, Lainey, Le Bars, Le Bars, Le Dizès, Le Dizès, Leblanc, Leblanc, Leweke, Leweke, Lundgren, M. Le Bars, Malkus, Mason, McAlister, Meunier, Moore, Munk, P. Le Gal, P. Maubert, Pierrehumbert, Poincaré, Potylitsin, Rieutord, Roy, Seyed-Mahmoud, Seyed-Mahmoud, Shangli, Sipp, Sipp, Thess, Touma, Vladimirov, Waleffe, Widnall, Williams   +60 more
core   +4 more sources

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source