Results 51 to 60 of about 71,185 (259)

Interaction between low tidal volume ventilation strategy and severity of acute respiratory distress syndrome: a retrospective cohort study

open access: yesCritical Care, 2019
Background Although low tidal volume is strongly recommended for acute respiratory distress syndrome (ARDS), whether or not the benefit varies according to the severity of ARDS remains unclear.
Yanfei Shen   +5 more
doaj   +1 more source

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

open access: yesAdvanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang   +13 more
wiley   +1 more source

Predictive Registry Optimization of Molecular Adsorbates on Solid Surfaces

open access: yesAngewandte Chemie, EarlyView.
Local C–H “spikes” from a π‐conjugated backbone lock into graphene “pockets”. A geometric registry score turns images obtained by scanning tunneling microscopy at the solid/liquid interface into atomic‐scale adsorption models, enabling assignment of surface atropisomers in large π‐conjugated molecules.
David A. Hofmeister   +7 more
wiley   +2 more sources

Intraoperative low tidal volume ventilation strategy has no benefits during laparoscopic cholecystectomy

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2017
Background and Aims: Benefits of intraoperative low tidal volume ventilation during laparoscopic surgery are not conclusively proven, even though its advantages were seen in other situations with intraoperative respiratory compromise such as one-lung ...
Vandna Arora   +4 more
doaj   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

open access: yesAdvanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo   +7 more
wiley   +1 more source

Effects of high-tidal-volume mechanical ventilation on the expression of PX receptor and inflammatory response in lung tissue of rats

open access: yesEuropean Journal of Inflammation, 2018
Ventilator-induced lung injury is a severe complication mainly caused from mechanical ventilation (MV), associated with the upregulation of inflammation response. The mechanism still remains unclear. This study aims to explore the effects of pathological
Jia Jia, Hanyu Qin, Bin Zang
doaj   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

open access: yesAdvanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen   +12 more
wiley   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

Effects of positive end-expiratory pressure and recruitment maneuvers in a ventilator-induced injury mouse model. [PDF]

open access: yesPLoS ONE, 2017
Positive-pressure mechanical ventilation is an essential therapeutic intervention, yet it causes the clinical syndrome known as ventilator-induced lung injury.
Laura A Cagle   +6 more
doaj   +1 more source

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