Results 81 to 90 of about 523,422 (382)

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang   +16 more
wiley   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

open access: yesAdvanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li   +11 more
wiley   +1 more source

Impact of global seismicity on sea level change assessment

open access: yes, 2005
We analyze the effect of seismic activity on sealevel variations, by computing the time-dependent vertical crustal movement and geoid change due to coseismic deformations and postseismic relaxation effects.
Melini, D., Piersanti, A.
core   +1 more source

Coastal Sea Level Measurements Using a Single Geodetic GPS Receiver [PDF]

open access: yes, 2013
This paper presents a method to derive local sea level variations using data from a single geodetic-quality Global Navigation Satellite System (GNSS) receiver using GPS (Global Positioning System) signals.
Haas, Rüdiger   +2 more
core   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li   +8 more
wiley   +1 more source

Vertical Crustal Motion Derived from Satellite Altimetry and Tide Gauges, and Comparisons with DORIS Measurements [PDF]

open access: yes, 2010
A somewhat unorthodox method for determining vertical crustal motion at a tide-gauge location is to difference the sea level time series with an equivalent time series determined from satellite altimetry, To the extent that both instruments measure an ...
Beckley, B. D.   +2 more
core   +1 more source

An 11-year validation of wave-surge modelling in the Irish Sea, using a nested POLCOMS-WAM modelling system [PDF]

open access: yes, 2010
In the future it is believed that extreme coastal flooding events will increase (in frequency and intensity) as a result of climate change. We are investigating the flood risks in the eastern Irish Sea posed by extreme storm events.
Brown, Jennifer M.   +2 more
core   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

Lunar nodal tide in the Baltic Sea

open access: yesOceanologia, 2001
The nodal tide in the Baltic Sea was studied on the basis of the Stockholm tide-gauge readings for 1825-1984; data from the tide gauge at Swinoujscie for the same period provided comparative material. The Stockholm readings are highly accurate and are
Andrzej Wróblewski
doaj  

Comparison of two data acquisition protocols for tide gauge sensors at Imbituba port – Santa Catarina State

open access: yesAgropecuária Catarinense, 2021
The Santa Catarina Tide Gauge Network (SCTGN) is a continuous sea level monitoring system to support fishery, aquaculture, and navigation in general.  Deployed in the state of Santa Catarina, Brazil, the initiative started in 2012 with one tide gauge at ...
Luis Hamilton Pospissil Garbossa   +3 more
doaj  

Home - About - Disclaimer - Privacy