Results 61 to 70 of about 66,358 (264)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Кубанский научный медицинский вестник, 2017 Aim. To explore the possibility for a temporary compression of the perforation hole by endobiliary stenting in close proximity of papillotomy anastomosis. Materials and methods.
V. V. YURCHENKO, R. B. OSUMBEKOV
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
$p$-adic Dual Shearlet Frames [PDF]
Sahand Communications in Mathematical Analysis, 2019 We introduced the continuous and discrete $p$-adic shearlet systems. We restrict ourselves to a brief description of the $p$-adic theory and shearlets in real case.
Mahdieh Fatemidokht +1 more
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Kirkman Equiangular Tight Frames and Codes [PDF]
IEEE Transactions on Information Theory, 2014 An equiangular tight frame (ETF) is a set of unit vectors in a Euclidean space whose coherence is as small as possible, equaling the Welch bound. Also known as Welch-bound-equality sequences, such frames arise in various applications, such as waveform design and compressed sensing.
John Jasper +2 more
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
APL QuantumProtocols of quantum information science often realize in terms of specially selected states. In particular, such states are used to perform measurements at the final stage of a protocol.
Alexey E. Rastegin
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A Unified Transform for LTI Systems—Presented as a (Generalized) Frame
EURASIP Journal on Advances in Signal Processing, 2006 We present a set of functions in and show it to be a (tight) generalized frame (as presented by G. Kaiser (1994)). The analysis side of the frame operation is called the continuous unified transform. We show that some of the well-known transforms (such
Van den Hof Paul MJ +2 more
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An Image Reconstruction Method Based on Total Variation and Wavelet Tight Frame for Limited-Angle CT
IEEE Access, 2018 Limited-angle computed tomography (CT) reconstruction problem is an ill-posed inverse problem. Currently, regularized CT reconstructions are usually considered by incorporating the total variation (TV) norm of an image into data fidelity term.
Xiaoqiang Luo, Wei Yu, Chengxiang Wang
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