Results 71 to 80 of about 525,025 (272)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
An Image Reconstruction Method Based on Total Variation and Wavelet Tight Frame for Limited-Angle CT
IEEE Access, 2018 Limited-angle computed tomography (CT) reconstruction problem is an ill-posed inverse problem. Currently, regularized CT reconstructions are usually considered by incorporating the total variation (TV) norm of an image into data fidelity term.
Xiaoqiang Luo, Wei Yu, Chengxiang Wang
doaj +1 more source
Applied and Computational Harmonic Analysis, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
APL QuantumProtocols of quantum information science often realize in terms of specially selected states. In particular, such states are used to perform measurements at the final stage of a protocol.
Alexey E. Rastegin
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Unified Transform for LTI Systems—Presented as a (Generalized) Frame
EURASIP Journal on Advances in Signal Processing, 2006 We present a set of functions in and show it to be a (tight) generalized frame (as presented by G. Kaiser (1994)). The analysis side of the frame operation is called the continuous unified transform. We show that some of the well-known transforms (such
Van den Hof Paul MJ +2 more
doaj +1 more source
K-g-fusion frames in Hilbert spaces
Journal of Inequalities and Applications, 2020 K-g-fusion frames are generalizations of fusion frames, K-fusion frames and g-fusion frames. In this paper, we present some new characterizations of K-g-fusion frames and tight K-g-fusion frames, and give several properties of K-g-fusion frames by means ...
Yongdong Huang, Yuanyuan Yang
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source