Results 51 to 60 of about 2,233,482 (303)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Automatic inversion of fracture parameters in tight gas reservoirs based on gas production profile [PDF]
Youqicang pingjia yu kaifaAccurately determining hydraulic fracture parameters is crucial for guiding the design of fracturing treatments and predicting single-well production.
XIAO Honglin, BU Chunliang, HOU Fu, TANG Huiying, WANG Yiyun, LUO Shangui
doaj +1 more source
Gas Slippage in Tight Formations
, 2023 In order to address the gas slippage for flow through tight formation, with a very low porosity (less than 10%) and permeability in micro-Darcy range, a series of single-phase gas flow experiments were conducted. Two different gases (N2 and He) were used to carry out many single-phase experiments at different overburden and pressure drops and were ...
Sherif Fakher, Abdelaziz Khlaifat
openaire +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Frontiers in Earth Science, 2022 Natural gas in the tight sandstone reservoirs in Member two of the Upper Triassic Xujiahe Formation in the Western Sichuan Depression of the Sichuan Basin has complex geochemical characteristics, and the origin and source of the tight gas are revealed ...
Xiaoqi Wu +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Tight maps, a classification [PDF]
, 2014 This thesis concerns the classification of tight totally geodesic maps between Hermitian symmetric spaces of noncompact type. In Paper I we classify holomorphic tight maps.
Hamlet, Oskar
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source