Results 41 to 50 of about 430,784 (291)

Quantitative assessment of the sweet spot in marine shale oil and gas based on geology, engineering, and economics: A case study from the Eagle Ford Shale, USA

Energy Strategy Reviews, 2021
Shale oil and gas have become important areas of petroleum exploration and development. Successful shale oil and gas exploration depends on the accurate evaluation of sweet spots, which are the commercial targets.
Lianhua Hou, Caineng Zou, Zhichao Yu, Xia Luo, Songtao Wu, Zhongying Zhao, Senhu Lin, Zhi Yang, Lijun Zhang, Dingwei Wen, Jingwei Cui   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Oil Prices and the Impact of Rising Economies [PDF]

, 2014
•The first commercial oil well was drilled in Romania in 1857, since then oil has been playing a crucial role in the global economy. •High oil prices can slow economic growth, cause inflationary pressures and create global imbalances.
Tabor, Metasebia
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Reservoir and development characteristics of the Da'anzhai tight oil in Sichuan Basin, SW China

Petroleum Research, 2019
The oil in the Jurassic Da'anzhai reservoirs in the Sichuan Basin is unconventional tight oil, which accumulated in or near source rocks, and did not experience extensive migration in a large-scale long distance. The first submember, second submember and
Yongjun Wang, Min Tong, Yuanhui Sun, Yuanzhong Zhang, Dawei Yuan   +4 more
doaj   +1 more source

A comparative study of geological conditions of tight oils in China and USA

Shiyou shiyan dizhi, 2022
On the basis of formulating and perfecting the definition and connotation of tight oil, a comparative study was carried out on the basin formation, hydrocarbon generation, hydrocarbon preservation and reservoir formation for 9 tight oil basins of China ...
Qun LUO, Yang GAO, Zeyuan ZHANG, Shichen WANG, Lan HONG, Wenyu MA, Qian XU   +6 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The occurrence of tight oil in the Chang 8 lacustrine sandstone of the Huaqing area, Ordos Basin, China: Insights into the content of adsorbed oil and its controlling factors

Journal of Natural Gas Geoscience, 2022
Tight oil is a great potential resource for unconventional oil exploration and development. Determining the content of adsorbed tight oil in sandstone reservoirs and the factors controlling its content is crucial for the evaluation and development of ...
Chao Li, Guojun Chen, Xiaotian Li, Qianshan Zhou, Zhaotong Sun   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source