Results 131 to 140 of about 277,783 (271)

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

The Impact of Pollution on Cultural Heritage in the Historic Centre of Porto, Portugal

Urban Science
Pollution is a constant threat to cultural heritage, mainly affecting its constituent materials, and it is urgent to implement mitigation and adaptation measures to prevent pollution.
Fátima Matos Silva, Marta Arreiol, Ana Fragata   +2 more
doaj   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

Archaeological Findings of the 16th–17th Centuries from the Town of Trypillia and Its Historical Topography

Київські історичні студії
The article analyses the informative potential of archaeological materials of the 16–17th centuries from the territory of the town of Trypillia to reconstruct its historical topography.
Mariia Videiko
doaj   +1 more source

Triangle Tiling V: Tilings by a tile with integer sides

, 2012
An N-tiling of triangle ABC by triangle T is a way of writing ABC as a union of N triangles congruent to T, overlapping only at their boundaries. The triangle T is the "tile". The tile may or may not be similar to ABC. We wish to understand possible tilings by completely characterizing the triples (ABC, T, N) such that ABC can be N-tiled by T.
openaire   +2 more sources

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

3D‐MOF‐Lattice Inspired Programmable Metamaterials Based on Reconfigurable Polyhedral Origami

Advanced Science, EarlyView.
A novel metamaterial design strategy: inspired by MOFs crystal networks, creating reconfigurable modular polyhedral units to overcome the limitations of traditional materials. These modules exhibit adjustable stiffness, bistability, and Poisson's ratio that can be adjusted from negative to positive values.
Xi Kang, Yangqin Zhang, Hongshuang Fan, Ziyan Xu, Yue Dong, Bing Li   +5 more
wiley   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

Advanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li, Tianqi Su, Bin Zhang, Wenkai Han, Sibin Zhang, Guiyin Sun, Yuwei Cong, Xin Chen, Jiping Qi, Yujie Wang, Shiguang Zhao, Hongxue Meng, Peng Liang, Xin Gao   +13 more
wiley   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Tiling groups for Wang tiles

, 2001
Nous utilisons les groupes de pavages et fonctions de hauteur pour les pavages de régions du plan par des tuiles de Wang, qui sont des carrés aux cotés colorés ( nous voulons que les cotés partagées par deux carrés aient la même couleur). Nous définissons un ensemble de tuiles comme étant non-ambigü s'il contient toutes les tuiles équivalentes l ...
Moore, Cristopher, Rapaport, Ivan, Rémila, Eric   +2 more
openaire   +1 more source