Results 131 to 140 of about 8,941,456 (288)

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Exploring the Feasibility of Novel 3D Polyhedrally-Tiled Computing Arrays

IEEE Access
Polyhedral tiled computing arrays (PTCAs) are a largely unexplored paradigm in which the assembly of high performance computing (HPC) structures may be achieved by the multidimensional tiling of particular polyhedral modules, each housing computing ...
Chris Crispin-Bailey, Pakon Thuphairo, Steven Wright, Anthony Moulds, Jim Austin   +4 more
doaj   +1 more source

History of the German Element in Texas from 1820-1850, and Historical Sketches of the German Texas Singers' League and Houston Turnverein from 1853-1913

, 1913
This volume covers the German Element in Texas, 1820-1850; an historical sketch of the Texas German Singers' League (Texas Staats Saengerbund), 1853-1913; an historical sketch of the Houston Turnverein, 1854-1913; German Day celebrations in Houston, 1889-
Tiling, Moritz, 1851-1916
core  

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Tiling automaton: a Computational Model for Recognizable Two-dimensional Languages

, 2007
Two-dimensional languages can be recognized by tiling systems. A tiling system becomes an effective device for recognition when a scanning strategy on pictures is fixed.
ANSELMO, Marcella, Anselmo, M, Anselmo, M., GIAMMARRESI D, Madonia, M, Giammarresi, D, GIAMMARRESI, DORA, MADONIA M., Madonia, M.   +8 more
core   +1 more source

Automatic Estimation of Solar Rooftops and Power Generation From Publicly Available Satellite Imagery Through Georeferencing and Large-Scale Support

IEEE Access
Rooftop photovoltaic (PV) power systems constitute a viable alternative energy technology that can significantly reduce electricity costs. The rapid increase in installations has led to a mismatch between planned power generation and actual electricity ...
John Sullivan, Apichon Witayangkurn
doaj   +1 more source

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

Advanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun, Jin Pyo Kang, Ho‐Sung Lee, Ik‐Hyeon Jeon, Ki‐Ju Park, Won‐Ju Cho, Seung‐heon Chris Baek, Joo‐Hyung Chae, Hamin Park   +8 more
wiley   +1 more source

Inspection and test plan for the execution of internal plaster systems and tiling and paving

, 2022
Cílem bakalářské práce je představení vnitřních omítkových systémů a obkladů a dlažeb. Bakalářská práce se skládá z teoretické a praktické části. V teoretické části jsou představeny nejběžnější druhy vnitřních omítek a obkladů a dlažeb. Dále jsou popsány
Trung Thanh Nguyen
core  

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

Advanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi, Antonio Ferraro, Francesco Coccimiglio, Tiziana Ritacco, Alberto Astolfo, Michele Giocondo, Vincenzo Formoso, Raffaele Giuseppe Agostino, Francesco Iacoviello, Ioannis Papakonstantinou, Alessandro Olivo   +10 more
wiley   +1 more source

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

Advanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang, Jun Liu, Qi Zhao, Huilong Yin, Angang Yang, Minhua Zheng, Rui Zhang   +6 more
wiley   +1 more source