Results 21 to 30 of about 14,213 (249)

A TILLING Platform for Functional Genomics in Brachypodium distachyon. [PDF]

PLoS ONE, 2013
The new model plant for temperate grasses, Brachypodium distachyon offers great potential as a tool for functional genomics. We have established a sodium azide-induced mutant collection and a TILLING platform, called "BRACHYTIL", for the inbred line Bd21-
Marion Dalmais, Sébastien Antelme, Séverine Ho-Yue-Kuang, Yin Wang, Olivier Darracq, Madeleine Bouvier d'Yvoire, Laurent Cézard, Frédéric Légée, Eddy Blondet, Nicolas Oria, Christelle Troadec, Véronique Brunaud, Lise Jouanin, Herman Höfte, Abdelafid Bendahmane, Catherine Lapierre, Richard Sibout   +16 more
doaj   +1 more source

Discovery of induced point mutations in maize genes by TILLING

BMC Plant Biology, 2004
Background Going from a gene sequence to its function in the context of a whole organism requires a strategy for targeting mutations, referred to as reverse genetics.
Enns Linda C, Codomo Christine A, Bowers Elisabeth, Young Kim, Burtner Chris, Springer Nathan, Weil Clifford, Reynolds Steven H, Till Bradley J, Odden Anthony R, Greene Elizabeth A, Comai Luca, Henikoff Steven   +12 more
doaj   +1 more source

TILLING & EcoTILLING in tomato : harvesting artificial and natural genetic diversity [PDF]

, 2011
Mutations in genes controlling specific traits of interest are widely used in plant breeding to introduce particular characteristics in commercial varieties.
Gady, A.L.F.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Main Tilling [PDF]

, 2022
The article covers materials related to the main tilling of the cotton-growing zone, reasons for the appearance of a dense soil layer, measures to eliminate the compacted soil layer by deep loosening of subsurface horizon.
Khojiev, A. K. (A), Bibutov, N. S. (N)
core  

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

Arthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen, Yasuo Nagafuchi, Kristina Lend, Seyam Alemyar, Herman Kasper Glas, Gerdur Gröndal, Bjorn Gudbjornsson, Espen A. Haavardsholm, Kim Hørslev Petersen, Jon Lampa, Merete Lund Hetland, Dan Nordström, Mike Nurmohamed, Mikkel Østergaard, Anna Rudin, Marte Schrumpf Heiberg, Tuulikki Sokka‐Isler, Till Uhlig, Josien Veris‐van Dieren, Ronald van Vollenhoven, Tom Huizinga, Marcel JT Reinders, Sytske Anne Bergstra, Erik van den Akker, Rachel Knevel   +24 more
wiley   +1 more source

Bioremediation of a Crude Oil Polluted Tropical Mangrove Environment

Journal of Applied Sciences and Environmental Management, 2004
A combination of bioaugumentation with hydrocarbon utilizing indigenous bacteria, biostimulation with agricultural fertilizer (NPK 15:15:15) and tilling were employed as remedial options for 20 weeks in a crude oil polluted tidal plain dominated by ...
L.O. ODOKUMA, A.A. DICKSON
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

High Resolution Melt (HRM) analysis is an efficient tool to genotype EMS mutants in complex crop genomes

Plant Methods, 2011
Background Targeted Induced Loci Lesions IN Genomes (TILLING) is increasingly being used to generate and identify mutations in target genes of crop genomes.
Lochlainn Seosamh Ó, Amoah Stephen, Graham Neil S, Alamer Khalid, Rios Juan J, Kurup Smita, Stoute Andrew, Hammond John P, Østergaard Lars, King Graham J, White Phillip J, Broadley Martin R   +11 more
doaj   +1 more source

Mutational Analysis of a Wheat O-methyltransferase Involved in Flavonoid Metabolism

Plants, 2022
Methylated flavones, and tricin in particular, have been implicated in protecting wheat plants against a variety of biotic and abiotic stresses. Methylated flavones are produced via O-methylation of the hydroxyl groups in flavones, which is catalyzed by ...
Alexander B. Cain, Shu Yu, Li Tian
doaj   +1 more source