Results 41 to 50 of about 27,747 (293)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Dysautonomia: an Explanation for the Medically Unexplained?

European Journal of Case Reports in Internal Medicine, 2016
Objective: To identify dysautonomia as a collection of conditions with variable presentation that may be mistaken for medically unexplained symptoms. Methods: Case series.
Senthil Chandrasekaram, Ranga H Fernando, Vikram Aaarella, Emily T Mudenha, Devaka J Fernando   +4 more
doaj   +1 more source

Diagnostic and societal impact of implementing the syncope guidelines of the European Society of Cardiology (SYNERGY study)

BMC Medicine, 2023
Background Syncope management is fraught with unnecessary tests and frequent failure to establish a diagnosis. We evaluated the potential of implementing the 2018 European Society of Cardiology (ESC) Syncope Guidelines regarding diagnostic yield ...
M. Ghariq, W. B. van den Hout, O. M. Dekkers, M. Bootsma, B. de Groot, J. G. J. Groothuis, M. P. M. Harms, M. E. W. Hemels, E. C. A. Kaal, E. M. Koomen, F. J. de Lange, S. Y. G. Peeters, I. A. van Rossum, J. H. W. Rutten, E. W. van Zwet, J. G. van Dijk, R. D. Thijs, on behalf of the SYNERGY Consortium   +17 more
doaj   +1 more source

Cardiovascular Response to Posture Changes: Multiscale Modeling and in vivo Validation During Head-Up Tilt

Frontiers in Physiology, 2022
In spite of cardiovascular system (CVS) response to posture changes have been widely studied, a number of mechanisms and their interplay in regulating central blood pressure and organs perfusion upon orthostatic stress are not yet clear.
Matteo Fois, Simona Vittoria Maule, Marta Giudici, Matteo Valente, Luca Ridolfi, Stefania Scarsoglio   +5 more
doaj   +1 more source

Mechanisms of Vasovagal Syncope in the Young: Reduced Systemic Vascular Resistance Versus Reduced Cardiac Output

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundSyncope is a sudden transient loss of consciousness and postural tone caused by cerebral hypoperfusion. The most common form is vasovagal syncope (VVS).
Julian M. Stewart, Marvin S. Medow, Richard Sutton, Paul Visintainer, David L. Jardine, Wouter Wieling   +5 more
doaj   +1 more source

A Case of Orthostatic Tachycardia Syndrome Presenting with Panic Attack during Tilt Table Testing

, 2011
A 26-year-old woman experienced syncope on standing 2–3 times a year for more than 15 years. The attack was typically associated with palpitations and frequently accompanied by a feeling of intense fear.
H. Kataoka
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Orthostatic intolerance as a potential contributor to prolonged fatigue and inconsistent performance in elite swimmers

BMC Sports Science, Medicine and Rehabilitation, 2022
Background Athletic underperformance is characterized by fatigue and an inability to sustain a consistent exercise workload. We describe five elite swimmers with prolonged fatigue and athletic underperformance.
Lindsay S. Petracek, Ella F. Eastin, Ian R. Rowe, Peter C. Rowe   +3 more
doaj   +1 more source

Comparison of a 20 degree and 70 degree tilt test in adolescent myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients

Frontiers in Pediatrics, 2023
IntroductionDuring a standard 70-degree head-up tilt test, 90% of adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) develop an abnormal reduction in cerebral blood flow (CBF).
C. (Linda) M. C. van Campen, Peter C. Rowe, Frans C. Visser   +2 more
doaj   +1 more source