Results 101 to 110 of about 18,801,342 (289)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Yothu Yindi's Wityana Marika and Mangatjay Yunupingu performing at WOMADelaide, Adelaide, 1993 [picture] /

, 2004
Part of: Tim Webster collection of photographs of Australian dance and dancers.; Title from acquisition documentation.; Acquired in digital format; access copies available online.; Mode of access: Internet via World Wide ...
Webster, Tim (Timothy James), 1965-
core  

TIM-4 expression is associated with enhanced endocytic ability in APC from the SI.

, 2016
Cells were isolated from the SI LP of CT treated mice and enriched for CD11c+ cells by magnetic selection. (A) CD11c+ cells were co-cultured with e670 labelled (AB-e670) or unlabelled apoptotic bodies (AB) for 1 hour and TIM-4+ and TIM-4− macrophages ...
Franca Ronchese (78627), Alfonso J. Schmidt (3158931), Kerry L. Hilligan (3158934), Lisa M. Connor (3158937)   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tim-3+ Treg cells from HNSCC TIL secrete more cytokines. from Novel Effector Phenotype of Tim-3⁺ Regulatory T Cells Leads to Enhanced Suppressive Function in Head and Neck Cancer Patients

, 2018
For IL-10, Granzyme B and IFN-γ quantification, bulk TIL were stimulated in vitro with anti-CD3/CD28 beads and protein transport inhibitor (BD GolgiPlugTM) for 6h.Cells were then stained for intracellular cytokine expression by flow cytometry.
Lawrence P. Kane (6989672), Robert L. Ferris (10263132), Kevin Chen (264284), Elizabeth L. McMichael (15003750), Gulidanna Shayan (14095584), Jing Li (10611), Raghvendra Srivastava (3543131), Binfeng Lu (182721), Zhuqing Liu (1980976)   +8 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Peculiarities of inhibitory receptor expression on effector and regulatory T cells in the context of immune checkpoint inhibitor therapy

Сибирский научный медицинский журнал
Inhibitory receptors PD-1, TIM-3, LAG-3, etc. – “immune checkpoints” – are expressed by activated effector T cells in order to limit the intensity of the immune response.
E. V. Batorov, P. V. Vasilchenko, E. R. Chernykh   +2 more
doaj   +1 more source

Knife sharpening man with a grinder, operating from the back of a minivan in Queen Street, Queen Victoria Market, Melbourne, 23 July 2002 [picture] /

, 2002
Title devised by cataloguer based on information from the photographer.; Part of the collection: Scenes from the Queen Victoria Market, Melbourne, 2002.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide ...
Webster, Tim (Timothy James), 1965-
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tin Son watch and clock stall at the Queen Victoria Market, Melbourne, 11 November 2002 [picture] /

, 2002
Title devised by cataloguer based on information from the photographer.; Part of the collection: Scenes from the Queen Victoria Market, Melbourne, 2002.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide ...
Webster, Tim (Timothy James), 1965-
core