Results 291 to 300 of about 17,630,315 (317)
Dysfunctional Decidual CD4<sup>+</sup>T Cells Induce Recurrent Pregnancy Loss via Palmitoylation-Dependent Tim-3 Lysosomal Sorting and Degradation. [PDF]
Adv Sci (Weinh)Cui L +6 more
europepmc +1 more source
Expression of the inhibitory checkpoints LAG-3, TIM-3, and PD-1 in NK cells and T cells in acute myeloid leukemia: preserved expression of LAG-3 is associated with patient survival. [PDF]
Cancer Immunol ImmunotherValhondo I +14 more
europepmc +1 more source
New Therapeutic Targets TIGIT, LAG-3 and TIM-3 in the Treatment of Advanced, Non-Small-Cell Lung Cancer. [PDF]
Int J Mol SciKabut J +2 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
TIM‐3 Expression in Endometriosis
American Journal of Reproductive ImmunologyEndometriosis is a prevalent chronic gynecological disease linked to immune dysfunction. The protein T‐cell immunoglobulin and mucin domain‐containing protein 3 (TIM‐3) plays a crucial role in immune system balance.
José Lourenço Reis +5 more
semanticscholar +3 more sources
TIM-3: An update on immunotherapy.
International Immunopharmacology, 2021T cell immunoglobulin and mucin domain 3 (TIM-3) was originally found to be expressed on the surface of Th1 cells, acting as a negative regulator and binding to the ligand galectin-9 to mediate Th1 cell the apoptosis. Recent studies have shown that TIM-3 is also expressed on other immune cells, such as macrophages, dendritic cells, and monocytes.
Lizhen Zhao +4 more
semanticscholar +3 more sources
TIM-3 regulates microglial function
Nature Reviews Drug DiscoverySarah Crunkhorn
semanticscholar +2 more sources
Asia-Pacific Journal of Clinical Oncology, 2020
AbstractAimTo characterize the distribution of T cell immunoglobulin mucin‐domain‐containing‐3 (Tim‐3) within the exhausted T cells in patients with newly diagnosed acute myeloid leukemia (AML) and AML in complete remission.MethodsTim‐3 expression and coexpression with PD‐1, CD244, and CD57 in CD3+, CD4+, and CD8+T cells were analyzed by multicolored ...
Jiaxiong Tan +7 more
openaire +2 more sources
AbstractAimTo characterize the distribution of T cell immunoglobulin mucin‐domain‐containing‐3 (Tim‐3) within the exhausted T cells in patients with newly diagnosed acute myeloid leukemia (AML) and AML in complete remission.MethodsTim‐3 expression and coexpression with PD‐1, CD244, and CD57 in CD3+, CD4+, and CD8+T cells were analyzed by multicolored ...
Jiaxiong Tan +7 more
openaire +2 more sources
Science Translational Medicine, 2023
T cell immunoglobulin and mucin-containing molecule 3 (Tim-3), expressed in dysfunctional and exhausted T cells, has been widely acknowledged as a promising immune checkpoint target for tumor immunotherapy.
Shuaiya Ma +26 more
semanticscholar +1 more source
T cell immunoglobulin and mucin-containing molecule 3 (Tim-3), expressed in dysfunctional and exhausted T cells, has been widely acknowledged as a promising immune checkpoint target for tumor immunotherapy.
Shuaiya Ma +26 more
semanticscholar +1 more source
Current Opinion in Immunology, 2006
T cell immunoglobulin and mucin domain (TIM)-3 is a molecule expressed on terminally differentiated murine Th1 cells but not on Th2 cells. Identification of galectin-9 as a ligand for TIM-3 has now firmly established the TIM-3-galectin-9 pathway as an important regulator of Th1 immunity and tolerance induction. TIM-3 is similarly expressed on human Th1
Ana C, Anderson, David E, Anderson
openaire +2 more sources
T cell immunoglobulin and mucin domain (TIM)-3 is a molecule expressed on terminally differentiated murine Th1 cells but not on Th2 cells. Identification of galectin-9 as a ligand for TIM-3 has now firmly established the TIM-3-galectin-9 pathway as an important regulator of Th1 immunity and tolerance induction. TIM-3 is similarly expressed on human Th1
Ana C, Anderson, David E, Anderson
openaire +2 more sources