Results 101 to 110 of about 23,327,589 (260)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Stability analysis and stabilization for singular systems with multiple time-varying delay

open access: yes, 2010
This paper considers the problem associated with the stability analysis and stabilization for singular systems with multiple time-varying delays. The delay-dependent stability criterion and the method of designing state feedback stabilization controller ...
Li, Chunji   +3 more
core  

Investigation of a Generalized Frequency Domain Method for Modeling Time-Varying Loads on Antennas [PDF]

open access: yes, 2019
Within traditional antenna design, the behavior of the antenna can be dictated by its physical dimensions and their proportions to a wavelength. Traditional electrically small antennas in particular face many limitations on factors such as their gain ...
Palmer, Ashley
core  

Neural Coding and Feature Extraction of Time-Varying Signals [PDF]

open access: yes, 2002
What are the neuronal codes that the brain uses to represent information? This constitutes one of the most fascinating and challenging questions in Neuroscience.
Kreiman, Gabriel Alejandro
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Decentralized robust output tracking for large-scale systems with time-varying uncertainties

open access: yes, 1996
This paper investigates the problem of decentralized robust output tracking control for a class of large-scale uncertain systems.
Lu LL(卢立磊)   +2 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Expected optimal feedback with Time-Varying Parameters [PDF]

open access: yes
In this paper we derive, by using dynamic programming, the closed loop form of the Expected Optimal Feedback rule with time varying parameter. As such this paper extends the work of Kendrick (1981, 2002, Chapter 6) for the time varying parameter case ...
Hans M. Amman   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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