Results 121 to 130 of about 23,327,589 (260)

Synchronization of Fractional Chaotic Systems with Time-Varying Perturbation

Fractal and Fractional
Aiming at the synchronization problem of fractional time-varying perturbation systems, an improved WRBF neural network was proposed based on the wavelet function and radial basis function (RBF).
Shaofu Wang
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Time-varying coefficient models and measurement error [PDF]

, 2007
This thesis is concerned with presenting and developing modeling approaches which allow for a time-varying effect of covariates by using time-varying coefficients. The different approaches are compared in simulation studies.
Breitner, S., Breitner, Susanne
core   +1 more source

Estimating Deterministically Time-Varying Variances in Regression Models [PDF]

The problem of structural change justifiably attracts considerable attention in econometrics. A number of different paradigms have been adopted ranging from structural breaks which are sudden and rare to time varying coefficient models which exhibit ...
George Kapetanios
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Controller Design for Continuous-Time Linear Control Systems with Time-Varying Delay

Mathematics
This paper addresses the controller design problem for linear systems with time-varying delays. By constructing a novel Lyapunov–Krasovskii functional incorporating delay-partitioning techniques, we establish delay-dependent stability criteria for the ...
Hongli Yang, Lijuan Yang, Ivan Ganchev Ivanov   +2 more
doaj   +1 more source

On the L₂ stability of time-varying linear systems

, 1971
Two theorems giving sufficient conditions for a class of linear time-varying systems to be stable in the L2 sense are given. These theorems give better bounds than those in [4]
Vidyasagar, M.
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source