Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Energy characteristics of impact-induced stress waves and their damage effects on coal
Meitan xuebaoClarifying the effects of dynamic stress waves on coal-damage behavior supports the development of water-free coal-permeability enhancement methods. This study examines the time–frequency and energy characteristics of stress waves generated by impact ...
Zeqi WANG +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Method for Suppressing Non-Stationary Interference in the Main-Lobe Based on a Multi-Polarized Array
SensorsTo suppress non-stationary main-lobe interference, we utilized the waveform information of the transmitted signal and proposed an interference suppression method based on a multi-polarized array without the need for calculating the target parameters ...
Jie Wang +4 more
doaj +1 more source
Time-Frequency Analysis of Mechanical Vibrations of the Dry Type Power Transformer Core
, 2011 S. Borucki
openalex +1 more source
Cross-sectional analysis characterizing the use of rank preserving structural failure time in oncology studies: changes to hazard ratio and frequency of inappropriate use [PDF]
, 2023 Vinay Prasad +2 more
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
GPU Implementation of the Improved CEEMDAN Algorithm for Fast and Efficient EEG Time-Frequency Analysis. [PDF]
Sensors (Basel), 2023 Wang Z, Juhasz Z.
europepmc +1 more source
Multimodal real-time frequency tracking of cantilever arrays in liquid environment for biodetection: Comprehensive setup and performance analysis [PDF]
, 2021 Annalisa De Pastina +6 more
openalex +1 more source