Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Adaptive Approach to Time-Frequency Analysis of AE Signals of Rocks. [PDF]
Lukovenkova O +2 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Time-Frequency Analysis of ERG With Discrete Wavelet Transform and Matching Pursuits for Glaucoma. [PDF]
Sarossy M +4 more
europepmc +1 more source
Estimation of sand water content using GPR combined time-frequency analysis in the Ordos Basin, China [PDF]
Yongshuai Yan, Yan Yajing, Zhao Guizhang
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Enhancing Time-Frequency Analysis with Zero-Mean Preprocessing. [PDF]
Jin S, Johansson P, Kim H, Hong S.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Cortical activity during the wind-up of flexion reflex and pain: a magnetoencephalographic study using time-frequency analysis. [PDF]
Taniguchi T +7 more
europepmc +1 more source
Banach-Gelfand triples and applications in time-frequency analysis
Veit-Severin Bannert
openalex +1 more source

