Results 201 to 210 of about 6,742,308 (298)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

DEP-CEEMDAN-MPE-INHT a time-frequency analysis method for noisy blasting seismic waves with adaptive noise suppression and endpoint processing. [PDF]

Sci Rep
Sun M, Wu J, Wang YF, Lu YN, Yu FD.
europepmc   +1 more source

Public attention, oil and gold markets during the COVID-19: Evidence from time-frequency analysis. [PDF]

Resour Policy, 2022
Li S, Xu Q, Lv Y, Yuan D.
europepmc   +1 more source

TIME/FREQUENCY ANALYSIS OF TERRESTRIAL IMPACT CRATER RECORDS [PDF]

, 2006
Heon-Young Chang
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Time frequency analysis of elastic wave PSO OMP for defects in flat steel of down conductors. [PDF]

Sci Rep
Zhang J, Liu W, Bao M, Yang P, Liu X, Fu Z.   +5 more
europepmc   +1 more source

The fast continuous wavelet transformation (fCWT) for real-time, high-quality, noise-resistant time-frequency analysis. [PDF]

Nat Comput Sci, 2022
Arts LPA, van den Broek EL.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

MVB fault diagnosis based on time-frequency analysis and convolutional neural networks. [PDF]

Sci Rep
Song X, Li Z, Liu Y.
europepmc   +1 more source